Clinical Trials in Tennessee

Showing 5281-5300 of 20,239 trials

Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer

NCT06140407

This phase II trial studies how well pembrolizumab after standard treatment with radiation plus the following chemotherapy drugs: cisplatin or carboplatin, plus etoposide works in treating patients with limited stage small cell lung cancer (LS-SCLC). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving pembrolizumab after standard treatment with radiation plus chemotherapy may increase the ability of the immune system to fight LS-SCLC.

Limited Stage Lung Small Cell CarcinomaStage I Lung CancerStage II Lung Cancer+1 more

Vanderbilt-Ingram Cancer Center1 participantsStarted Feb 2024

Nashville, Tennessee, United States

RECRUITINGPhase 329 miles

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

NCT07006675

Two arm, pragmatic, randomized controlled multicenter Phase III noninferiority trial evaluating the efficacy of standard pain management without NSAIDs (Group 1) vs. standard pain management plus up to 6 weeks of NSAIDs (Group 2) in the treatment of tibial shaft fractures.

Tibial FracturesPain

Major Extremity Trauma Research Consortium1,000 participantsStarted May 2021

Indianapolis, Indiana, United States • Indianapolis, Indiana, United States • Baltimore, Maryland, United States +11 more locations

Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

Find Trials by Condition in Tennessee

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

Botulinum Toxin Treatment of Glabellar Lines: Efficacy and Safety Study III (BLESSIII)

Research Study To See How Well An Eye Drop (SURF-200) Works, What Side Effects There Are, And To Compare It With Vehicle In Subjects With An Episodic Flare-Up of Dry Eye Disease

A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (Core OLE)

Study to Assess the Safety, Tolerability, Pharmacokinetics and Immunogenicity of AK006 in Healthy Subjects and Subjects With Chronic Spontaneous Urticaria

Assessment of Early Pregnancy MAB Completion

Study of Bone Growth in the Sacroiliac Joint After Minimally Invasive Surgery With Titanium Implants

A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator in Adult Participants With Narcolepsy Type 1

Infant Formula in Infants and Children With Cow's Milk Allergy

RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency

Fractionated CO2 Laser With and Without Clobetasol for Treatment of Vulvar Lichen Sclerosus

Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

A Mind-Body Intervention for Hot Flash Management

A Multi-Center Trial of Androgen Suppression With Abiraterone Acetate, Leuprolide, PARP Inhibition and Stereotactic Body Radiotherapy in Prostate Cancer

Prostate Oncologic Therapy While Ensuring Neurovascular Conservation (POTEN-C)

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Evaluation of the Safety and Efficacy of Ang-(1-7) to Enhance Cognitive Function in Participants Undergoing CABG