Clinical Trials in Tennessee

Showing 2481-2500 of 17,345 trials

Suture Repair vs Mesh Repair for Incisional Hernia

NCT05599750

The goal of this randomized controlled trial is to compare the difference in quality of life at one year postoperatively for patients undergoing incisional hernia repair with mesh versus suture repair using modern techniques. The main question it aims to answer are: • Determine if primary suture repair is non-inferior to mesh repair for incisional hernias 2-6cm with respect to quality of life using the HerQLes summary score at one year postoperatively.

Incisional Hernia

Clayton Petro154 participantsStarted Nov 2022

Gainesville, Florida, United States • Chicago, Illinois, United States • Cleveland, Ohio, United States +2 more locations

Active Not RecruitingPhase 229 miles

A Study to Evaluate AI-09 In Participants With Glabellar Lines

NCT07321834

Phase 2 clinical study to evaluate the efficacy, safety, and tolerability of AI-09, a Ready-to-Use Liquid Injectable Botulinum Toxin.

Glabellar Lines

Eirion Therapeutics Inc.68 participantsStarted Dec 2025

Aventura, Florida, United States • West Palm Beach, Florida, United States • New Orleans, Louisiana, United States +2 more locations

Active Not RecruitingPhase 129 miles

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Adults With Solid Malignancies

NCT05006794

This is a Phase I open-label, multi-center study of zamzetoclax (formerly GS-9716) tested either as monotherapy or in combination with other anti-cancer agents in patients with advanced solid malignancies. Primary objectives are to define the maximum tolerated dose (MTD) or maximum administered dose of zamzetoclax, and characterize the safety and tolerability of zamzetoclax as monotherapy and in combination with anti-cancer therapies.

Solid Malignancies

Gilead Sciences145 participantsStarted Sep 2021

Aurora, Colorado, United States • Tampa, Florida, United States • Grand Rapids, Michigan, United States +10 more locations

Suture Repair vs Mesh Repair for Incisional Hernia

A Study to Evaluate AI-09 In Participants With Glabellar Lines

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Adults With Solid Malignancies

Find Trials by Condition in Tennessee

Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

A Study of CT-388 in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

[18F]PI-2620 Phase 3 Histopathological Study

A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies

First-in-Human, Phase I, Open-label, Multicenter, Dose Escalation Clinical Study

Conservative Surgery in Treating Patients With Low-Risk Stage IA2 or IB1 Cervical Cancer

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.