Clinical Trials in Seattle

Showing 6841-6860 of 9,312 trials

Cisplatin and Nab-paclitaxel for (N2) Defined NSCLC

NCT02276560

The purpose of this research study is to determine whether giving cisplatin and nab-paclitaxel before surgery will reduce the presence of disease in certain areas of the lung at the time of surgery.

Stage IIIA Non-Small Cell Lung Cancer

UNC Lineberger Comprehensive Cancer Center1 participantsStarted Jan 2015

Tampa, Florida, United States • Atlanta, Georgia, United States • Kansas City, Kansas, United States +6 more locations

COMPLETEDPhase 1< 1 mile

Dose-Escalation Study of GSK2126458

NCT00972686

P3K112826 is a Phase I, first-time-in-human dose escalation study in subjects with refractory malignancy. The primary objective of this study is to determine the recommended Phase II dose of GSK2126458 based on safety and tolerability, pharmacokinetics, pharmacodynamics and preliminary evidence of clinical activity. Secondary objectives are to characterize the pharmacokinetics of GSK2126458; and to explore relationships between GSK2126458 pharmacokinetics, pharmacodynamics, response prediction biomarkers and clinical endpoints.

Solid Tumours

GlaxoSmithKline79 participantsStarted Aug 2009

San Francisco, California, United States • New Brunswick, New Jersey, United States • Chapel Hill, North Carolina, United States +6 more locations

Cisplatin and Nab-paclitaxel for (N2) Defined NSCLC

Dose-Escalation Study of GSK2126458

Find Trials by Condition in Seattle

Bortezomib and Vorinostat in Treating Patients With Multiple Myeloma Who Have Undergone Autologous Stem Cell Transplant

Positron Emission Tomography in Predicting Response in Patients Who Are Undergoing Treatment With Pemetrexed Disodium and Cisplatin With or Without Surgery for Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma

Nursing Management of Irritable Bowel Syndrome (IBS) 2008

Reaching Out to Adolescents With Depression

Atorvastatin (Lipitor) Therapy in Patients With Clinically Isolated Syndrome (CIS) at Risk for Multiple Sclerosis

A Pilot Study of BMS-512148 in Subjects With Type 2 Diabetes

A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN)

Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration

Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes

PREventative Study Against URate-lowering Drug-induced Gout Exacerbations 1

A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's Disease

Study of the Safety and Effectiveness of Rilonacept for the Prevention of Gout Flares

Impact of Dietary Intervention on Weight Change in Subjects With Type 2 Diabetes

Lymphedema After Surgery in Patients With Endometrial Cancer, Cervical Cancer, or Vulvar Cancer

Efficacy and Safety Study of Benralizumab Added to High-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled Asthma

Roll-Over Protocol To Provide Atv And/Or Truvada For Extended Access

Phase II Study Evaluating Efficacy, Safety and Pharmacokinetics of Pasireotide in Patients With Dumping Syndrome