Clinical Trials in Seattle

Showing 4021-4040 of 9,312 trials

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

NCT00079417

This phase III trial is studying how well giving carboplatin and vincristine together with standard local ophthalmic therapy works in treating children with intraocular retinoblastoma. Drugs used in chemotherapy, such as carboplatin and vincristine, work in different ways to stop tumor from dividing so they stop growing or die. It is not yet known whether neoadjuvant chemotherapy combined with standard local ophthalmic therapy is effective in treating intraocular retinoblastoma.

Intraocular Retinoblastoma

Children's Oncology Group28 participantsStarted Dec 2005

Los Angeles, California, United States • Chicago, Illinois, United States • Boston, Massachusetts, United States +7 more locations

UNKNOWNPhase 2< 1 mile

Phase 2, Open-Label, Single Arm Study, With BST-236 in Adults With R/R AML or Higher-Risk MDS

NCT04749355

An open label multi center study to assess the safety and efficacy of BST-236 as single agent in adult patients unfit for standard therapy with Acute Myeloid Leukemia (AML) or higher-risk (HR) Myelodysplastic Syndromes (MDS) who fail to respond or relapsed following first line therapy. Approximately 20 adult patients with relapsed and/or refractory AML and approximately 20 adult patients with relapsed and/or refractory HR MDS, will be enrolled into the study. Patients will be treated with 1-2 induction courses and 2-4 maintenance courses. All patients will be followed for 1 year in the study and additional 1 year post study follow-up.

AML, AdultMDSRelapse/Recurrence+1 more

BioSight Ltd.40 participantsStarted Nov 2021

Shreveport, Louisiana, United States • Houston, Texas, United States • Charlottesville, Virginia, United States +1 more locations

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

Phase 2, Open-Label, Single Arm Study, With BST-236 in Adults With R/R AML or Higher-Risk MDS

Find Trials by Condition in Seattle

Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label Extension

A Safety Study of SGN-LIV1A in Breast Cancer Patients

Effect of HSV-2 Suppressive Therapy on Sexual Behavior

An Investigational Immuno-therapy Safety and Effectiveness Study of Nivolumab in Combination With Brentuximab Vedotin to Treat Non-Hodgkin Lymphomas

Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD

Phase 1/1b Study of MGCD516 in Patients With Advanced Cancer

Allo vs Hypomethylating/Best Supportive Care in MDS (BMTCTN1102)

A Study of Maribavir Compared to Valganciclovir to Treat Cytomegalovirus Infections in People Who Have Received Stem Cell Transplants

TAC Versus TC for Adjuvant Breast Cancer

A Safety, Tolerability and Preliminary Efficacy Study of CC-90011 in Combination With Venetoclax and Azacitidine in R/R Acute Myeloid Leukemia and Treatment-naïve Participants Not Eligible for Intensive Therapy

Dose Ranging Study of Rimegepant (BMS-927711) for the Acute Treatment of Migraine

Expanded Access Protocol Using 131I-MIBG

Evaluation of the Roadsaver Stent Used in Conjunction With the Nanoparasol Embolic Protection System for Carotid Artery Stenosis

An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026)

Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

A Study to Test if TEV-48574 is Effective in Relieving Asthma

A Study of Verinurad and Allopurinol in Patients With Chronic Kidney Disease and Hyperuricaemia