Clinical Trials in San Francisco

Showing 7841-7860 of 12,991 trials

COMPLETEDPhase 1< 1 mile

Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease

NCT01973543

Safety study of AADC gene transfer (VY-AADC01) in subjects with Parkinson's disease.

Parkinson's Disease

Neurocrine Biosciences15 participantsStarted Oct 2013

San Francisco, California, United States • Pittsburgh, Pennsylvania, United States

COMPLETEDNA< 1 mile

Study of Time-restricted Eating on Weight Loss.

NCT03393195

This is a randomized controlled trial studying the effects of time-restricted eating (TRE) on weight loss in obese humans. Obesity is the number one risk factor for type 2 Diabetes Mellitus (T2DM), and numerous studies demonstrate that weight loss is an effective strategy to prevent T2DM and improve the metabolic health of people diagnosed with T2DM. Unfortunately, classical calorie restriction diets often fail to produce long-term weight loss due to low compliance, reduced resting metabolic rate (RMR), and other factors. Therefore, novel dieting techniques must be explored in order to successfully treat obesity and prevent T2DM. Studies in mice provide compelling evidence that feeding/fasting cycles can be altered to produce beneficial effects on weight loss and metabolic health markers in the absence of calorie restriction. Limited research in human subjects suggests that this feeding paradigm may translate to human health as well, however, more research needs to be done in order to confirm this hypothesis. This study will determine if TRE can lead to weight loss in obese human subjects. Secondary outcomes include changes in body composition, HOMA-IR, hormonal and biochemical serum markers, RMR, and total energy expenditure (TEE).

ObesityInsulin Resistance

University of California, San Francisco137 participantsStarted Jul 2018

San Francisco, California, United States

Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease

Study of Time-restricted Eating on Weight Loss.

Find Trials by Condition in San Francisco

Pilot Study on the Tolerability of Dietary Dried Plum

Open-label Safety Study of E/C/F/TAF (Genvoya®) in HIV-1 Positive Patients With Mild to Moderate Renal Impairment

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination +/- Ribavirin in Adolescents and Children With Chronic HCV-Infection

Paleolithic Diets vs T2D and Improvements in the Metabolic Syndrome

STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Multi-Center, Randomized, Open-Label Study of G/P +/- RBV for NS5A + SOF Previously Treated GT1 HCV Subjects

The Blood Pressure and Metabolic Effects of Nebivolol in Hypertensive Patients With Impaired Glucose Tolerance or Impaired Fasting Glucose

Post Traumatic Stress Disorder (PTSD), Sleep Disordered Breathing And Genetics: Effects On Cognition

Study Assessing PTI-428 Safety, Tolerability, Pharmacokinetics and Effect in Subjects With Cystic Fibrosis

Efficacy of Alicaforsen in Pouchitis Patients Who Have Failed to Respond to at Least One Course of Antibiotics

A Comparison of 188-0551 Spray Versus Vehicle Spray in Subjects With Plaque Psoriasis

T.E.A.M. Feasibility and Efficacy Study 2.0

Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria

A Study to Evaluate Tolerability and Participants Preference Between Mirabegron and Tolterodine Extended Release (ER) in Participants With Overactive Bladder (OAB)

Telerehabilitation in the Home Versus Therapy In-Clinic for Patients With Stroke

Study Testing Radium-223 Dichloride in Relapsed Multiple Myeloma

ANG1005 in Patients With Recurrent High-Grade Glioma

A Study to Evaluate Gluten Challenge on Immune Responses in Subjects With Celiac Disease