Clinical Trials in San Francisco

Showing 6761-6780 of 12,991 trials

Multimodal MRI Characteristics of Psychotherapy Response in Late Life Depression

NCT02440815

The specific focus of this study is to gather data regarding the effects of a psychological therapy known as Problem Solving Therapy (PST) on cerebral blood flow (CBF), cortical gray matter (GM) atrophy, subcortical white matter (WM) lesion burden, and measures of cognitive function in subjects with Late Life Major Depressive Disorder (LLD). This research goal will be achieved by recruiting 110 individuals over the age of 65 with LLD. The primary outcomes will be change in CBF, change in GM atrophy, change in WM lesion, change in cognitive function, and change in depression severity from baseline to the end of 12 weeks of PST.

Major Depressive Disorder

University of California, San Francisco108 participantsStarted Nov 2015

San Francisco, California, United States

COMPLETEDPhase 1/2< 1 mile

Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)

NCT02440789

The purpose of this study was to find out about the safety of sirolimus in individuals with HIV infection who were also being treated with ART. The investigators wanted to learn whether sirolimus decreases inflammation and immune activation in the body; whether sirolimus changes the level of HIV in the participants' blood; and how sirolimus interacts with ART in the blood. Sirolimus is approved by the Food and Drug Administration (FDA) to prevent organ rejection in patients aged 13 years and older receiving kidney transplants. Sirolimus had also been used for the prevention of complications after stem cell transplants and as a treatment for certain kinds of cancers in HIV-infected patients.

HIV-1 Infection

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections32 participantsStarted Dec 2015

San Francisco, California, United States • Washington D.C., District of Columbia, United States • Miami, Florida, United States +7 more locations

Multimodal MRI Characteristics of Psychotherapy Response in Late Life Depression

Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)

Find Trials by Condition in San Francisco

GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Biobanking of Rett Syndrome and Related Disorders

Natural History of Rett Syndrome & Related Disorders

The Use of Inhaled Aztreonam in Children With a Tracheostomy Tube and Pseudomonas

Validation of PSFS in Carpal Tunnel Syndrome

Study to Evaluate the Safety and Efficacy of Relamorelin in Participants With Diabetic Gastroparesis Study 02

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

B-mode Ultrasound Imaging in Detecting Early Liver Cancer

Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiform

SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants

Acthar for Treatment-Resistant or Treatment-Intolerant Proteinuria

A Study to Evaluate Safety and Efficacy of Panobinostat in Participants With Primary Myelofibrosis

Study to Evaluate the Safety and Efficacy of JTE-051 in Subjects With Moderate to Severe Plaque Psoriasis

A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01

A Study To Investigate Tanezumab In Patients With Interstitial Cystitis/ Painful Bladder Syndrome

Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies

Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)

Open Label, Phase III Study of NABI-IGIV 10% [Immune Globulin Intravenous(Human), 10%] In Subjects With Primary Immune Deficiency Disorders (PIDD)