Clinical Trials in San Francisco

Showing 2301-2320 of 11,161 trials

Model-based Electrical Brain Stimulation

NCT05327387

Neuropsychiatric disorders are a leading cause of disability worldwide with depressive disorders being one of the most disabling among them. Also, millions of patients do not respond to current medications or psychotherapy, which makes it critical to find an alternative therapy. Applying electrical stimulation at various brain targets has shown promise but there is a critical need to improve efficacy. Given inter- and intra-subject variabilities in neuropsychiatric disorders, this study aims to enable personalizing the stimulation therapy via i) tracking a patient's own symptoms based on their neural activity, and ii) a model of how their neural activity responds to stimulation therapy. The study will develop the modeling elements needed to realize a model-based personalized system for electrical brain stimulation to achieve this aim. The study will provide proof-of-concept demonstration in epilepsy patients who already have intracranial electroencephalography (iEEG) electrodes implanted for their standard clinical monitoring unrelated to this study, and who consent to being part of the study.

Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring

University of Southern California25 participantsStarted Feb 2022

Los Angeles, California, United States • San Francisco, California, United States

RECRUITING< 1 mile

Clinical Procedures to Support Research in ALS

NCT03489278

The purpose of the Clinical Procedures To Support Research (CAPTURE) study is to utilize information collected in the medical record to learn more about a disease called amyotrophic lateral sclerosis (ALS) and related disorders.

Amyotrophic Lateral SclerosisALS-Frontotemporal DementiaPrimary Lateral Sclerosis+1 more

University of Miami1,200 participantsStarted Feb 2018

Irvine, California, United States • Palo Alto, California, United States • San Francisco, California, United States +8 more locations

Model-based Electrical Brain Stimulation

Clinical Procedures to Support Research in ALS

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Assessing Brain Metabolism Using MRS With Deuterated Glucose

HLA Demographics Study in Adults With Type 1 Diabetes

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

UCSF PANC Cyst Registry

Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol Use

An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

EASE: The Materna Prep Pivotal Study

Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Childcare Healthy Beverage Access, Food and Beverage Intake, and Obesity

Clinical Effectiveness Assessment of VeriStrat® Testing and Validation of Immunotherapy Tests in NSCLC Subjects

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)

A Patient Registry Study for Patients Treated With Voretigene Neparvovec in US

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules

Short-course Regimens for the Treatment of Pulmonary Tuberculosis