Clinical Trials in San Antonio

Showing 3001-3020 of 12,572 trials

Rectal Misoprostol as a Hemostatic Agent During Abdominal Myomectomy

NCT03064568

Purpose is to identify if misoprostol in addition to local vasopressin decreases blood loss when compared to vasopressin alone, which is our current practice at this time. The study will be double-blinded with neither the patient nor the researcher knowing whether the placebo or the misoprostol was given. We will monitor patients for decrease in hemoglobin and hematocrit, need for transfusion, and operative time among other measures of perioperative morbidity to see if the addition of misoprostol makes a significant difference. We will also observe patients to see if there are any side effects of misoprostol that make its use undesirable.

Myomectomy; Surgical Blood Loss

The University of Texas Health Science Center at San Antonio18 participantsStarted Oct 2016

San Antonio, Texas, United States • San Antonio, Texas, United States • San Antonio, Texas, United States

COMPLETEDPhase 1< 1 mile

TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers

NCT04306900

This is a phase 1/1b study of TTX-030 in combination therapy, an antibody that inhibits CD39 enzymatic activity, leading to accumulation of pro-inflammatory adenosine triphosphate (ATP) and reduction of immunosuppressive adenosine, which may change the tumor microenvironment and promote anti-tumor immune response. This trial will study the safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor activity of TTX-030 in combination with immunotherapy and/or standard chemotherapies.

Solid Tumor, Adult

Trishula Therapeutics, Inc.185 participantsStarted Mar 2020

Scottsdale, Arizona, United States • Duarte, California, United States • Los Angeles, California, United States +29 more locations

Rectal Misoprostol as a Hemostatic Agent During Abdominal Myomectomy

TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers

Find Trials by Condition in San Antonio

Development and Validation of Harbinger Health Test for Early Cancer Detection

Enlighten Study: The EV-ICD Post Approval Registry

Study of Obeldesivir to Treat Nonhospitalized Adults With Acute Respiratory Syncytial Virus (RSV) Infection

A Study to Evaluate Safety and Tolerability of CVL-231 (Emraclidine) in Adult Participants With Schizophrenia

Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care in mRCC (KEYNOTE-679/ECHO-302)

Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial

A Study of Obexelimab in Patients With Systemic Lupus Erythematosus

Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis

A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease

Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)

A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma

Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell Transplant

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

A Long-term Follow-up Study of Patients Who Received VOR33

TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD

Prospective, Open-label, Non-significant Risk, Multicenter Study Comparing the Polyp Detection of the Study Device to That of the Colonoscopy Reference

A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)