Clinical Trials in Salt Lake City

Showing 1741-1760 of 14,325 trials

Improving Care for Rural Patients With Solid Tumors

NCT04916990

This study will assess if the CARES (Cancer Advocacy, Resources, Education and Support) intervention improves time to start of treatment after diagnosis and time to treatment completion for solid tumors (ex: lung, head, neck, thyroid, cervical, breast, bladder, colon, and rectal cancers) in rural patients.

Lung CancerHead and Neck CancerThyroid Cancer+5 more

University of Colorado, Denver320 participantsStarted Sep 2022

Aurora, Colorado, United States • Colorado Springs, Colorado, United States • Colorado Springs, Colorado, United States +11 more locations

COMPLETEDPhase 3< 1 mile

Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)

NCT03829319

The purpose of this study is to assess the safety and efficacy of pemetrexed + platinum chemotherapy + pembrolizumab (MK-3475) with or without lenvatinib (MK-7902/E7080) as first-line intervention in adults with metastatic nonsquamous non-small cell lung cancer. The primary study hypotheses state that: 1) the combination of lenvatinib + platinum doublet chemotherapy + pembrolizumab prolongs Progression-free Survival (PFS) as assessed by blinded independent central review (BICR) per modified Response Evaluation Criteria in Solid Tumors version 1.1 (RESIST 1.1) compared to matching placebo + platinum doublet chemotherapy + pembrolizumab, and 2) the combination of lenvatinib + platinum doublet chemotherapy + pembrolizumab prolongs Overall Survival (OS) compared to matching placebo + platinum doublet chemotherapy + pembrolizumab.

Nonsquamous Non-small Cell Lung Cancer

Merck Sharp & Dohme LLC761 participantsStarted Mar 2019

Mountain View, California, United States • New Haven, Connecticut, United States • Fort Lauderdale, Florida, United States +155 more locations

Improving Care for Rural Patients With Solid Tumors

Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)

Find Trials by Condition in Salt Lake City

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

Rate of Progression in USH2A-related Retinal Degeneration

Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

A Study to Assess Adverse Events and Effectiveness of IntraVenous Infusions of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

Randomized Study of the pdSTIM™ System in Failure to Wean Mechanically Ventilated Patients

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib

Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk

A Study of AL102 in Patients With Progressing Desmoid Tumors

A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)

Single Versus Dual Implant Fixation of Distal Femur Fractures

A Novel Multiplex ELISA Assay for Evaluating Patients With Microscopic Hematuria for Bladder Cancer

A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)

Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)

International CRDS Registry