Clinical Trials in Salt Lake City

Showing 4321-4340 of 16,694 trials

Hydrogen's Feasibility and Safety as a Therapy in ECPR

NCT05574296

The purpose of this project is to test the feasibility and safety of inhaled hydrogen gas (H2) administration as a rescue therapy during cardiac arrest requiring extracorporeal cardiopulmonary resuscitation (ECPR, i.e. mechanical circulatory support). Under exemption from informed consent, patients undergoing refractory cardiac arrest in the cardiac ICU at a participating center will be randomized to standard therapy with or without the administration of 2% hydrogen in gases administered via the ventilator and ECMO membrane for 72 hours.

Cardiac ArrestExtracorporeal Membrane OxygenationReperfusion Injury

Boston Children's Hospital53 participantsStarted Mar 2024

Washington D.C., District of Columbia, United States • Boston, Massachusetts, United States • Kansas City, Missouri, United States +1 more locations

COMPLETEDPhase 3187 miles

Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households

NCT03969212

Otherwise healthy index patients (IP) are randomized to either baloxavir marboxil or placebo if their influenza symptoms onset was within 48 hours of screening. Their households are enrolled within 24 hours of randomization if at least 1 household contacts (HHC) have not received influenza vaccine within 6 months of screening and if all HHC screen negative for influenza infection. The main endpoints are assessed based on multiple respiratory swabs, obtained from both IP and HHC up to 9 (+/-1) days post IP randomization, and through the assessment of symptoms.

Influenza

Hoffmann-La Roche4,138 participantsStarted Oct 2019

Birmingham, Alabama, United States • Pelham, Alabama, United States • Phoenix, Arizona, United States +139 more locations

Hydrogen's Feasibility and Safety as a Therapy in ECPR

Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households

Find Trials by Condition in Salt Lake City

A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration

Clinical Study of CMP-001 in Combination With Pembrolizumab or as a Monotherapy

A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial Myopathy

Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 1)

STEM-PD Open Label Extension (OLE)

Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Adults With Rheumatoid Arthritis

Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study In Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)

Human Amniotic Membrane On Venous Leg Ulcers In an Elderly Population

Study Testing Response Effect of KY1005 Against Moderate-to-Severe Atopic Dermatitis, The STREAM-AD Study

Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

Delivering Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention in Opioid Use Disorder

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

Predicting Local and Distant Recurrence in T1 Colorectal Cancer

A Phase II Study Using Rituximab Plus Venetoclax in the Front Line Treatment of Marginal Zone Lymphoma

Stage II/III Colorectal Cancer Recurrence

An Open-label Study of Povetacicept in Participants With Autoimmune Cytopenias

Abbott Vascular Medical Device Registry

Study to Evaluate the Safety and Effectiveness of GP0116