Clinical Trials in Portland

Showing 2661-2680 of 8,670 trials

Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer

NCT04121676

This study is an open-label, Phase 1, multicenter study to evaluate the safety, tolerability, PK, and PD profiles of AGEN2373 as a monotherapy and in combination with botensilimab (also known as AGEN1181), and to assess the maximum tolerated dose (MTD) in subjects with advanced solid tumors.

Advanced Cancer

Agenus Inc.91 participantsStarted Sep 2019

Los Angeles, California, United States • Aurora, Colorado, United States • Coral Gables, Florida, United States +9 more locations

Active Not RecruitingPhase 1/2< 1 mile

A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

NCT05885464

This is a Phase 1/2, multicenter, open-label study to evaluate the safety and efficacy of BEAM-201 in patients with relapsed/refractory T-ALL or T-LL. This study consists of Phase 1 dose-exploration cohorts, Phase 1 dose-expansion cohort(s), a Phase 1 pediatric cohort (will enroll patients ages 1 to \< 12 years), and a Phase 2 cohort.

Lymphoblastic LymphomaT-Cell Lymphoblastic Leukemia/LymphomaLymphoblastic Leukemia

Beam Therapeutics Inc.5 participantsStarted May 2023

Stanford, California, United States • Denver, Colorado, United States • Chicago, Illinois, United States +7 more locations

Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer

A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

Find Trials by Condition in Portland

Open-Label Extension Study of Upadacitinib in Adult Participants With Moderate to Severe Atopic Dermatitis

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response

The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)

Efficacy of a Multimodal Brain Health Intervention for Older African Americans

PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - S3 Intermediate

Predictive Factors for Medullary Thyroid Cancer Aggressiveness

CtDNA Based MRD Testing for NAC Monitoring in TNBC

AZD9291 (Osimertinib) Versus Platinum-Based Doublet-Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Benefits of Microcor in Ambulatory Decompensated Heart Failure

Emergency Department-Initiated Buprenorphine Validation Network Trial

FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study

A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).

Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers

EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)

Open-Label Extension Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis

Multi-Center Study of GSK2857916 in Combination With Pomalidomide and Dex

Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest Stage I or Stage II Huntington's Disease

A Study of TAK-861 in Participants With Narcolepsy Type 2