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Discover 21,047 clinical trials near Pittsburgh, Pennsylvania. Find research studies in your area.
Showing 15561-15580 of 21,047 trials
NCT00177957
The aims of this study are to: * Determine the risk factors for multidrug resistance in bloodstream isolates of Gram negative bacilli * Determine the mechanisms of multidrug resistance in bloodstream isolates of Gram negative bacilli * Determine the risk factors for failure of prompt clearance of the blood of Gram negative bacteria * Determine the survival of patients with Gram negative bacteremia * Determine if failure of prompt clearance of the blood of Gram negative bacteria is a predictor of mortality following this infection
NCT02124681
Current options to treat insulin resistance in diabetes are fairly limited. For this reason, novel treatments would represent a major progress. The generic drug hydroxychloroquine (HCQ) has poorly understood effects on blood sugar metabolism. In this study, the investigators will examine the mechanisms by which this drug affects glucose metabolism and which cells are affected. Findings emanating from this project will help establish whether HCQ may be a viable treatment for disorders of glucose metabolism.
NCT01221311
The current standard of care for benign bile duct strictures involves placement of multiple plastic stents under endoscopic and fluoroscopic guidance to progressively dilate or stretch it open. This approach necessitates multiple procedures which may extend over one year before the stricture is adequately dilated. The investigators propose a study comparing the standard approach of plastic stenting with the use of newer, fully coated metallic stents which are self-expandable, thereby permitting successful dilation of benign bile duct strictures with fewer procedures.