Clinical Trials in Pittsburgh

Showing 14541-14560 of 21,047 trials

Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix

NCT01580410

This randomized phase II trial is studying the side effects and how well giving oxaliplatin or mitomycin C directly into the abdomen after surgery works in treating patients with tumors of the appendix. Drugs used in chemotherapy, such as oxaliplatin and mitomycin C, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Heating a chemotherapy solution and infusing it directly into the abdomen may kill more tumor cells. Giving these treatments after surgery may kill any tumor cells that remain after surgery.

Carcinoma of the AppendixPrimary Peritoneal Cavity Cancer

Wake Forest University Health Sciences136 participantsStarted May 2009

Winston-Salem, North Carolina, United States • Pittsburgh, Pennsylvania, United States • Houston, Texas, United States

TERMINATEDPhase 3< 1 mile

A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke

NCT02072226

PRISMS is a double-blind, multicenter, randomized, Phase IIIb study to evaluate the efficacy and safety of intravenous (IV) alteplase in participants with mild acute ischemic strokes that do not appear to be clearly disabling. Participants will be randomized in a 1:1 ratio to receive within 3 hours of last known well time either 1) one dose of IV alteplase and one dose of oral aspirin placebo or 2) one dose of IV alteplase placebo and one dose of oral aspirin 325 milligrams (mg).

Stroke

Genentech, Inc.313 participantsStarted May 2014

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +85 more locations

Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix

A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke

Find Trials by Condition in Pittsburgh

RAPID: Reducing Pain; Preventing Depression

Study of the Safety and Immune Response of a Meningococcal Conjugate Vaccine Administered to Healthy Adolescents

Study to Assess the Immune Reactivity of the Liquid and Lyophilized Formulations of Palivizumab (MEDI-493, Synagis)

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

An Efficacy Study of Umeclidinium/Vilanterol With Tiotropium/Olodaterol in COPD Patients

Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Carboplatin and Paclitaxel

The Usability and Injection Time of the Physiolis Syringe and Autoinjector in Rheumatoid Arthritis Patients

An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate

Rebif® Versus Copaxone® in the Treatment of Relapsing Remitting Multiple Sclerosis

Multi-center, Randomized, Double-blind Efficacy and Safety of CD0271 0.3%/CD1579 2.5 % Topical Gel in Acne Vulgaris

Risk Factors for Developing a Blood Clot in Patients Who Are Undergoing Cancer Treatment for Newly Diagnosed Gliomas

Probiotics-Supplemented Feeding in Extremely Low Birth Weight Infants

Study to Assess the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of ABT-267 in HCV Infected Subjects

AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma

Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial

Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene

Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC)

Pivotal Study to Evaluate the Effectiveness of a Micro-coring Device Treating Moderate to Severe Facial Wrinkles