Clinical Trials in Pittsburgh

Showing 12401-12420 of 21,047 trials

A Study to Assess the Safety, Tolerability and Efficacy of OP0201 as an Adjunct Treatment for Acute Otitis Media in Infants and Children Aged 6 to 24 Months

NCT03818815

The purpose of this study is to develop a better understanding of the safety, tolerability and efficacy of intranasal OP0201 as an adjunct treatment to oral antibiotics for the treatment of Acute Otitis Media (AOM) in infants and children.

Acute Otitis Media

Novus Therapeutics, Inc103 participantsStarted Feb 2019

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

Doxorubicin Hydrochloride, Cyclophosphamide, and Pacltaxel With or Without Trastuzumab in Treating Women With HER2-Positive Node-Positive or High-Risk Node-Negative Breast Cancer

NCT00005970

This randomized phase III trial studies doxorubicin hydrochloride, cyclophosphamide, paclitaxel, and trastuzumab to see how well they work compared to combination chemotherapy alone in treating women with breast cancer that is human epidermal growth factor receptor 2 (HER2)-positive and has spread to the lymph nodes or high-risk and has not spread to the lymph nodes. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. It is not yet known whether combination chemotherapy is more effective with or without trastuzumab in treating breast cancer.

Breast AdenocarcinomaHER2 Positive Breast CarcinomaStage IA Breast Cancer AJCC v7+4 more

National Cancer Institute (NCI)3,436 participantsStarted May 2000

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Scottsdale, Arizona, United States +154 more locations

A Study to Assess the Safety, Tolerability and Efficacy of OP0201 as an Adjunct Treatment for Acute Otitis Media in Infants and Children Aged 6 to 24 Months

Doxorubicin Hydrochloride, Cyclophosphamide, and Pacltaxel With or Without Trastuzumab in Treating Women With HER2-Positive Node-Positive or High-Risk Node-Negative Breast Cancer

Find Trials by Condition in Pittsburgh

Safety Study on Stopping Anticoagulation Medication in Patients With a History of Atrial Fibrillation

To Study Generic Calcipotriene and Betamethasone Dipropionate Topical Foam, 0.005%/0.064%, in the Treatment of Psoriasis Vulgaris (Plaque Psoriasis).

A Randomized, Blinded, Multicenter Study to Evaluate NASHA/Dx for the Treatment of Fecal Incontinence

Expanded Access: Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE)

Extended-Release Naltrexone vs. Buprenorphine for Opioid Treatment

A Trial to Evaluate the Safety and Tolerability of Brexpiprazole in the Treatment of Participants With Bipolar I Disorder.

Sexual Function Trial of Overactive Bladder: Medication Versus PTNS

OIT and Xolair® (Omalizumab) in Cow's Milk Allergy

A Study That Compares the Extent to Which Apomorphine Becomes Available in the Body After Taking Either an Investigational Drug Containing Apomorphine or Apomorphine That is Injected Under the Skin in People With PD Complicated by "OFF" Episodes

Clinical and Device Functional Assessment of Real World ICD Patients

A Safety Study of NNZ-2566 in Pediatric Rett Syndrome

Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation

TMT Fusion Plate vs. Two Crossed Screws

Safety & Efficacy Study of Combination of Pembrolizumab and Lenalidomide, in Patients With Relapsed Non-Hodgkin and Hodgkin Lymphoma

Performance Improvement Program on Imaging II

Prospective Multicenter Trial to Compare Preformed vs Non Preformed Orbital Implants

A Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis