Clinical Trials in Pittsburgh

Showing 11921-11940 of 21,047 trials

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder

NCT02519543

In a previous study by Dr. Calkin, the principal investigator of this study, persons with bipolar disorder and either type II diabetes or insulin resistance were found to experience more severe symptoms of bipolar illness and a lower response to treatment, compared to persons with bipolar disorder who did not have type II diabetes or insulin resistance. To further explore these findings, the investigators have developed this study to see if treating insulin resistance (using metformin, a drug used to improve the body's use of insulin) may also help improve the symptoms of bipolar illness.

Bipolar Disorder

Cynthia Calkin50 participantsStarted Sep 2015

Pittsburgh, Pennsylvania, United States • Halifax, Nova Scotia, Canada

COMPLETEDPhase 2< 1 mile

Stereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR)

NCT01573702

\- Progression free survival after locally ablative therapy and erlotinib in EGFR patients progressed after EGFR-TKI therapy

Non Small Cell Lung Cancer

UNC Lineberger Comprehensive Cancer Center32 participantsStarted Dec 2012

San Francisco, California, United States • Aurora, Colorado, United States • Chapel Hill, North Carolina, United States +5 more locations

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder

Stereotactic Radiosurgery or Other Local Ablation Then Erlotinib in Epidermal Growth Factor Receptor (EGFR)

Find Trials by Condition in Pittsburgh

Bioimpedance Spectroscopy Versus Tape Measure in Prevention of Lymphedema (PREVENT)

Mechanistic Study of GSK3196165 Plus Methotrexate (MTX) in Subjects With Active Rheumatoid Arthritis

A Study to Investigate the Efficacy and Safety of GSK3196165 in Inflammatory Hand Osteoarthritis

A Dose Ranging Study of OPT-302 With Ranibizumab in Neovascular (Wet) AMD

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

A Study to Test if the Vaccine is Working Well in Chronic Obstructive Pulmonary Disease (COPD) Patients Aged 40 to 80 Years Old to Reduce Episodes of Worsening Symptoms and to Gather Further Information on Safety and Immune Response.

Ambrisentan in Patients With Porto-pulmonary Hypertension A Multicenter Open Label Trial

Pilot Study to Assess Palonosetron Versus Ondansetron as Rescue Medication in Subjects That Develop Postoperative Nausea and Vomiting (PONV) in the Postanesthesia Care Unit (PACU)

Clinical Study of Approved Contact Lenses

A Study of LY2157299 in Participants With Hepatocellular Carcinoma

Oral Sulopenem-etzadroxil/Probenecid Versus Ciprofloxacin for Uncomplicated Urinary Tract Infection in Adult Women

CP-690-550 Ointment For Chronic Plaque Psoriasis

Study of ANAVEX2-73 in Patients With Rett Syndrome

Albumin-Bound Paclitaxel and Gemcitabine in Patients With Untreated Stage IV or Recurrent Squamous Cell Lung Cancers

A Prospective, Multi-Center Evaluation of the ECHELON CIRCULAR Powered Stapler in Left-Sided Colorectal Anastomoses

To Determine The Efficacy and Safety of GDC-0449 in Patients With Basal Cell Nevus Syndrome (BCNS)

Comparison of Human Embryo Development Using Sequential and Single Media With Time-lapse Imaging

Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection