Clinical Trials in Pittsburgh

Showing 11041-11060 of 21,047 trials

NSABP Biospecimen Discovery Project

NCT01850628

This study is a biospecimen discovery project that will serve as a pilot for a comprehensive 'omics approach using fresh core biopsy tissue and blood samples for DNA and protein analysis, as well as paired tumor-normal exome DNA and RNA sequencing.

Breast Cancer

NSABP Foundation Inc50 participantsStarted Jul 2013

Gainesville, Florida, United States • St Louis, Missouri, United States • New York, New York, United States +2 more locations

UNKNOWNPhase 2/3< 1 mile

Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

NCT02065687

This randomized phase II/III trial studies how well paclitaxel, carboplatin, and metformin hydrochloride works and compares it to paclitaxel, carboplatin, and placebo in treating patients with endometrial cancer that is stage III, IV, or has come back. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Metformin hydrochloride may help paclitaxel and carboplatin work better by making cancer cells more sensitive to the drugs. It is not yet known whether paclitaxel and carboplatin is more effective with or without metformin hydrochloride in treating endometrial cancer.

Endometrial AdenocarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Serous Adenocarcinoma+9 more

Gynecologic Oncology Group469 participantsStarted Mar 2014

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Phoenix, Arizona, United States +428 more locations

NSABP Biospecimen Discovery Project

Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

Find Trials by Condition in Pittsburgh

Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed, Persistent or Recurrent Uterine, Ovarian, Fallopian Tube, or Peritoneal Cavity Cancer

Study of Denosumab as Adjuvant Treatment for Women With High Risk Early Breast Cancer Receiving Neoadjuvant or Adjuvant Therapy (D-CARE)

Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)

Onduo Virtual Diabetes Clinic Study

Phase 2 Study of Zevalin Versus Zevalin and Motexafin Gadolinium in Patients With Rituximab-Refractory Low-grade or Follicular B-cell Non-Hodgkin's Lymphoma

Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer

Fruit and Vegetable Extracts in Treating Patients With Stage I-IV, Stage IVA/IVB Head and Neck Cancer

Study of RV001V in Biochemical Failure Following Curatively Intended Therapy For Localized Prostate Cancer

Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic Dermatitis

Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC)

Characteristics of Eosinophilic Gastritis, Enteritis, and Colitis in a Multi-Site Cohort

A Study to Evaluate Treatment of Hepatitis C Virus Infection in Pediatric Subjects

Dose Escalation Study of UCART19 in Adult Patients With Relapsed / Refractory B-cell Acute Lymphoblastic Leukaemia

Fenestrated AAA Endovascular Graft Post-Approval Study

PTI-125 for Mild-to-moderate Alzheimer's Disease Patients

A First-in-Human Study of RPT193 in Healthy Volunteers and Patients With Atopic Dermatitis

ECG App Algorithms Clinical Validation Study

A Study of Alectinib in RET-rearranged Non-small Cell Lung Cancer or RET-mutated Thyroid Cancer