Clinical Trials in Pittsburgh

Showing 11001-11020 of 21,047 trials

Long-Term Extension of Previous rAvPAL-PEG Protocols in Subjects With PKU (PAL-003)

NCT00924703

This study is an extension of previous rAvPAL-PEG studies. Administration of rAvPAL-PEG will be continued to assess whether long-term dosing of rAvPAL-PEG is safe and can maintain reduced blood Phe concentrations in PKU subjects.

Phenylketonuria

BioMarin Pharmaceutical68 participantsStarted Jan 2010

Aurora, Colorado, United States • Gainesville, Florida, United States • Chicago, Illinois, United States +11 more locations

COMPLETEDPhase 3< 1 mile

Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis

NCT03401229

The aim of this present study is to investigate the use of benralizumab as treatment for severe nasal polyposis. The effect of benralizumab on nasal polyps will be assessed over a 56 weeks of treatment period in patients with severe bilateral nasal polyposis who are still symptomatic despite standard of care therapy, i.e current use of intranasal corticosteroids (INCS) and prior surgery and/or use of systemic corticosteroids. The first 200 patients that complete the 56-week treatment will have a 6 month follow-up (FU) period without dosing.

Nasal Polyposis

AstraZeneca413 participantsStarted Jan 2018

Birmingham, Alabama, United States • Fresno, California, United States • Huntington Beach, California, United States +96 more locations

Long-Term Extension of Previous rAvPAL-PEG Protocols in Subjects With PKU (PAL-003)

Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis

Find Trials by Condition in Pittsburgh

Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine

A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC

The (PIVOTAL) Study

Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves

Study of AMV564 in Patients With AML

Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL

Study of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012)

Hydroxychloroquine Monotherapy and in Combination With Azithromycin in Patients With Moderate and Severe COVID-19 Disease

A Safety Extension Study to Evaluate the Long-term Safety of QGE031 in Chronic Spontaneous Urticaria (CSU) Patients

Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHT

Phase I/II Study of hLL1-DOX in Relapsed NHL and CLL

Safety Study of LLF580 in Obese Volunteers

Study of Efficacy and Safety of Secukinumab 2 mL Auto-injector (300 mg) in Subjects With Moderate to Severe Plaque Psoriasis

A 12 Week Randomized Open Label Parallel Group Multicenter Study to Evaluate Bioequivalence of 20 mg Subcutaneous Ofatumumab Injected by Pre-filled Syringe or Autoinjector in Adult RMS Patients

Study of Efficacy and Safety of LOU064 in Inadequately Controlled Asthma Patients

Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthma

A Safety Study of IV Stem Cell-derived Extracellular Vesicles (UNEX-42) in Preterm Neonates at High Risk for BPD

Study to Compare QVM149 and Free Triple Combination of Salmeterol/Fluticasone + Tiotropium