Clinical Trials in Pittsburgh

Showing 10601-10620 of 21,047 trials

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

NCT02976038

This is a Phase 2 Open-Label extension study to evaluate the long term safety and tolerability of daily elamipretide injections in patients with genetically confirmed Primary Mitochondrial Disease who previously participated in the SPIMM-202 Clinical Trial

Primary Mitochondrial Disease

Stealth BioTherapeutics Inc.28 participantsStarted Dec 2016

San Diego, California, United States • Boston, Massachusetts, United States • Akron, Ohio, United States +1 more locations

COMPLETED< 1 mile

Study of Brain Cools Device in Patients Resuscitated From Cardiac Arrest

NCT03889340

This submission is a pilot in which the new IQool Warming System device will be used to maintain the temperature of adult patients in cardiac arrest within a range of within a range of 32°C to 38.5°C (89.6°F to 101.3°F). The IQool Warming System has received a 510 K Clearance by the FDA.

Cardiac Arrest With Successful Resuscitation

Adam Frisch38 participantsStarted May 2019

Pittsburgh, Pennsylvania, United States

COMPLETED< 1 mile

Deep Phenotyping in Patients With ALS

NCT02819765

This study aims to establish a biorepository and phenotyping database to investigate longitudinal changes in ALS subjects. Blood, including DNA and RNA, cerebrospinal fluid (CSF) and electrophysiologic measures will be collected every 6 months over 1 and a half years. The database and specimen repository will be made available to ALS researchers on a merit basis.

ALSMotor Neuron Disease

Barrow Neurological Institute32 participantsStarted Feb 2017

Phoenix, Arizona, United States • Grand Rapids, Michigan, United States • New York, New York, United States +4 more locations

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Study of Brain Cools Device in Patients Resuscitated From Cardiac Arrest

Deep Phenotyping in Patients With ALS

Find Trials by Condition in Pittsburgh

Randomized Endo-Vein Graft Prospective

Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury

A Study of Luspatercept (ACE-536) to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy

Study of BTK Inhibitor, Ibrutinib in Combination With Carfilzomib in Subjects With Relapsed and Refractory Multiple Myeloma

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)

Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi

T-Guard as Treatment for Steroid Refractory Acute GVHD (BMT CTN 1802)

Inhibiting Fatty Acid Synthase to Improve Efficacy of Neoadjuvant Chemotherapy

Vinflunine in Hormone Refractory Prostate Cancer (HRPC)

Restore EF Observational Study

Participant Reported Outcomes With Use of Trifarotene 50 μg/g Cream in the Treatment of Moderate Facial and Truncal Acne Vulgaris

Study of CAD-9303 in Subjects With Schizophrenia

Comparative Bioavailability of Risperidone

Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma

Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)

PREMOD2 With Near Infrared Spectroscopy Sub-study