Clinical Trials in Pittsburgh

Showing 9681-9700 of 21,047 trials

Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer

NCT02474173

This phase Ib trial studies the side effects and best dose onalespib when given together with paclitaxel in treating patients with triple negative breast cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced). Onalespib works by blocking proper processing of proteins that are important for cancer growth. This results in inability of these proteins to work properly. Paclitaxel kills breast cancer cells by interfering with their ability to divide. Giving onalespib together with paclitaxel may be better than giving either one alone in treating patients with breast cancer.

Advanced Breast CarcinomaMetastatic Breast CarcinomaStage III Breast Cancer AJCC v7+5 more

National Cancer Institute (NCI)31 participantsStarted Jan 2016

Lexington, Kentucky, United States • Columbus, Ohio, United States • Philadelphia, Pennsylvania, United States +1 more locations

COMPLETEDPhase 2/3< 1 mile

Study of Neural Responses Induced by Antidepressant Effects

NCT02674529

The proposed work aims to examine the neural changes associated with fast-acting antidepressant treatments in order to develop imaging-based biomarkers of treatment response for depression.

Major Depressive Disorder

Marta Peciña, MD PhD60 participantsStarted Sep 2016

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal Women

NCT02010593

This study will evaluate the safety of the dapivirine vaginal ring when inserts once every 4 weeks in postmenopausal women over 12 weeks of product use.

Human Immunodeficiency Virus

International Partnership for Microbicides, Inc.96 participantsStarted Dec 2013

Birmingham, Alabama, United States • Cleveland, Ohio, United States • Pittsburgh, Pennsylvania, United States

Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer

Study of Neural Responses Induced by Antidepressant Effects

Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal Women

Find Trials by Condition in Pittsburgh

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

A Prospective Multicenter Sample Collection Study Using Non-invasive Methods to Investigate Mutation Burden in Non-lesional Facial Skin of Patients With a Hx of Skin Cancer

VNS-induced Corticospinal Plasticity

VNS-supplemented Motor Retraining After Stroke

An Investigational Immuno-therapy Trial of Pomalidomide and Low-dose Dexamethasone With or Without Elotuzumab to Treat Refractory and Relapsed and Refractory Multiple Myeloma (ELOQUENT-3)

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®)

A Phase 2 Study of LY3209590 in Participants With Type 2 Diabetes Mellitus

Safety and Efficacy of Tenalisib (RP6530) in Combination With Romidepsin in Patients With Relapsed/Refractory T-cell Lymphoma

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration

Randomized, Double-Blind, Placebo-Controlled Trial, Followed by Single-Arm Treatment of PRO 140

Innovative Methods to Assess Psychotherapy Practices (imAPP)

A Study to Assess Long-term Safety, Tolerability and Efficacy of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

SUPERa Stenting After SUBintimal Crossing of TASC C-D Femoro-popliteal Lesions in CLI Patients

Fluvoxamine for Early Treatment of Covid-19 (Stop Covid 2)

Diagnostic Accuracy Of Forced Oscillation Technique To Detect Lung Function Anomalies

TMC114IFD3001 - Study Providing Continued Access to Treatment With Darunavir (DRV)/Ritonavir(Rtv) in HIV1 Infected Adults, Adolescents and Children Aged 3 Years or Above and Coming From Previous Company Sponsored Studies With DRV