Clinical Trials in Pittsburgh

Showing 7181-7200 of 21,047 trials

Epigenetic Effects on Traumatic Brain Injury Recovery

NCT04186429

Methylation of the brain-derived neurotrophic factor (BDNF) gene is involved in both the biological encoding of childhood adversity and neuroplasticity following traumatic brain injury (TBI). This research will characterize BDNF methylation during recovery from TBI in children and investigate this novel biomarker as a potential biological mechanism underlying the known association between childhood adversity and poorer neurobehavioral outcomes following TBI in childhood. Findings from this research will contribute to an improved understanding of why some children display good recovery following TBI, whereas many others suffer from chronic neurobehavioral impairments.

Traumatic Brain InjuryOrthopedic Injury

University of Pittsburgh401 participantsStarted Jul 2017

Pittsburgh, Pennsylvania, United States

COMPLETED< 1 mile

Clinical Evaluation of the i-STAT TBI Test

NCT04171960

The goal of this study is to evaluate the i-STAT TBI test to assist determining the need for a computed tomography (CT) scan in patients with suspected mild traumatic brain injury (TBI). Patients will be asked to provide a blood sample.

Traumatic Brain Injury

Abbott Point of Care1,106 participantsStarted Jul 2020

San Francisco, California, United States • Denver, Colorado, United States • Englewood, Colorado, United States +18 more locations

Epigenetic Effects on Traumatic Brain Injury Recovery

Clinical Evaluation of the i-STAT TBI Test

Find Trials by Condition in Pittsburgh

Spinal Plasticity to Enhance Motor Retraining After Stroke

Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer

A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1

A Study to Determine Dose and Regimen of Durvalumab as Monotherapy or in Combination With Pomalidomide With or Without Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)

VTX958 Versus Placebo for the Treatment of Moderate to Severe Psoriasis

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)

Clinical Trial To Evaluate Safety And Efficacy Of KT-301 (Formerly US-APR2020) In Subjects With Chronic Kidney Disease Stage IV

Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients

Study of AZD9291 Plus MEDI4736 Versus AZD9291 Monotherapy in NSCLC After Previous EGFR TKI Therapy in T790M Mutation Positive Tumours

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

ADVANCE- Automated Detection and Volumetric Assessment of ICH

Viz HCM (ECG Assist) Utilization Workflow Pilot

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients

Encore PFO Closure Device - The PerFOrm Trial