Clinical Trials in Pittsburgh

Showing 6161-6180 of 21,047 trials

Nitrite Supplementation in Long COVID Patients

NCT05618574

Potential benefits of a nitrate-rich juice supplement to improve skeletal muscle function and associated physical capacity will be studied in patients with Long COVID. Consenting patients with Long-COVID will be randomized to receive Beet-It nitrate beverage group versus a nitrate-depleted placebo beverage. Both groups will receive physical therapy at the long COVID Clinic at VAPHS with therapeutic goals to improve strength, balance, inspiratory, and aerobic capabilities. Physical therapy will last for 2 weeks and include 2 or 3 sessions with a physical therapist a week depending on each individual's exercise tolerance. These sessions can take place on-site or at home (or a hybrid combination) All participants will undergo functional assessments and tissue assessments before and after the 14-day study intervention.

Long COVIDCardiorespiratory Fitness

VA Office of Research and Development17 participantsStarted Dec 2023

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

APR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)

NCT03745716

A Phase III, multicenter, randomized study to compare the rate of complete response (CR) and duration of CR, in patients with TP53-mutated MDS who will receive APR-246 and azacitidine or azacitidine alone.

MDS

Aprea Therapeutics154 participantsStarted Jan 2019

Duarte, California, United States • Palo Alto, California, United States • New Haven, Connecticut, United States +24 more locations

Nitrite Supplementation in Long COVID Patients

APR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)

Find Trials by Condition in Pittsburgh

SG2501 Safety Study in Subjects with Relapsed or Refractory Hematological Malignancies and Lymphoma.

EVAS2 IDE Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study

A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders

A Study of INCB050465 in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a Bruton's Tyrosine Kinase (BTK) Inhibitor

Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy

Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women

Method Comparison Study for Measuring Potassium (K) and Ionized Calcium (iCa) in Blood

Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors

BIOTRONIK Conduction System Pacing With the Solia Lead

A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes

Study to Compare 2 Botulinum Type A Toxins in the Treatment of Glabellar Frown Lines

PF-06863135 As Single Agent And In Combination With Immunomodulatory Agents In Relapse/Refractory Multiple Myeloma

A Study of BMS-986442 With Nivolumab With or Without Chemotherapy in Solid Tumors and Non-small Cell Lung Cancer

Optical Coherence Tomography (OCT) Reference Data Collection Study (S-2015-3)

Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older

LOVE Trial: Limits On Vaginal Intercourse After Mid-urEthral Sling

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411

IMPROVE AKI Cluster-Randomized Trial