Clinical Trials in Pittsburgh

Showing 5761-5780 of 21,047 trials

Impairments That Affect Correct Inhaler Use in COPD

NCT06135324

INHALE is a one-year, multi-site observational research study funded by Viatris, with two aims: 1. Determine the prevalence of both cognitive impairment and impaired manual dexterity in stable out-patients with chronic obstructive pulmonary disease (COPD). 2. Assess the relationship of cognitive impairment and impaired manual dexterity with patient errors using current pMDIs, SMIs and/or DPIs.

COPD

COPD Foundation500 participantsStarted Dec 2023

Birmingham, Alabama, United States • Chicago, Illinois, United States • Burlington, Massachusetts, United States +6 more locations

COMPLETEDPhase 2< 1 mile

Cold-stored Platelet Early Intervention in TBI

NCT04726410

The Cold Stored Platelet Early Intervention in Traumatic Brain Injury (CriSP-TBI) trial is a proposed 3 year, open label, single center, randomized trial designed to determine the feasibility, efficacy, and safety of urgent release cold stored platelets (CSP) in patients with TBI requiring platelet transfusion. Patients will be randomized to receive either standard care or early infusion of urgent release cold stored platelets (CSP). The proposed pilot study will enroll at the University of Pittsburgh and will enroll approximately 100 patients. The primary outcome for the pilot trial is feasibility, with principal secondary clinical outcome of 6-month Extended Glasgow Outcome Scale (GOS-E).

Traumatic Brain Injury

Jason Sperry100 participantsStarted Mar 2022

Pittsburgh, Pennsylvania, United States

Impairments That Affect Correct Inhaler Use in COPD

Cold-stored Platelet Early Intervention in TBI

Find Trials by Condition in Pittsburgh

Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease

Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH)

APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

A Study of SEA-CD40 Given With Other Drugs in Cancers

Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma.

Pediatric ACL: Understanding Treatment Options

Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation

Evaluating the Safety and Effectiveness of the InnAVasc Graft for Dialysis Access in Patients With Kidney Failure

Lenalidomide (Revlimid®, CC-5013) in Subjects With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma

A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma

A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema

Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors

Adalimumab in JIA-associated Uveitis Stopping Trial

Trauma Informed Guilt Reduction Therapy

SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma