Clinical Trials in Pittsburgh

Showing 4201-4220 of 21,047 trials

Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty

NCT05017701

The aim of this research study is to gather data regarding the feasibility of the Bridge system for the management of pain following total hip arthroplasty (THA).

Pain, Postoperative

Masimo Corporation5 participantsStarted Apr 2022

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

NCT05412030

This is a Phase 2 clinical study to support the use of AFX3772 in healthy infants for the prevention of pneumococcal disease. The purpose of this study is to determine the safety, tolerability, and immunogenicity of 3 different formulations of AFX3772 compared with Prevnar 13 (PCV13) and Prevnar 20 (PCV). Part 1 is the dose escalation, lead-in portion of the study in which infants at each dose level will be randomized 3:1 in sequential cohorts of increasing doses of AFX3772 or PCV13. In Part 2, infants will be randomized to receive either one of two dose levels of AFX3772 or PCV20.

Pneumonia, BacterialPneumococcal InfectionsPneumonia, Pneumococcal

GlaxoSmithKline388 participantsStarted Jun 2022

Jonesboro, Arkansas, United States • Los Angeles, California, United States • Miami, Florida, United States +43 more locations

Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

Find Trials by Condition in Pittsburgh

Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

Study of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus

A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease

Staphylococcus Aureus Network Adaptive Platform Trial

Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

PMT for MDRO Decolonization

Study of Fordadistrogene Movaparvovec in Early Stage Duchenne Muscular Dystrophy

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

Retro Comparison of Subsidence Following Interbody Devices in Lumbar Spine

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer

A Study to Investigate the Antiviral Effect, Safety, Tolerability and Pharmacokinetics of VH3739937 in in Treatment-Naive Adults Living With HIV-1