Clinical Trials in Pittsburgh

Showing 3801-3820 of 18,077 trials

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

NCT06104969

This study is a platform study designed to efficiently test multiple biomarkers to identify diabetic foot ulcers (DFUs) with a higher potential for healing versus not healing that ultimately could be applied at the point of care to drive personalized management decisions, and to better inform clinical trials of wound healing interventions

Diabetic Foot UlcerDiabetic FootDiabetes

University of Michigan5,000 participantsStarted Jun 2023

Tucson, Arizona, United States • Los Angeles, California, United States • San Francisco, California, United States +5 more locations

COMPLETEDPhase 1/2< 1 mile

A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)

NCT05459129

This is a Phase Ib/II, open-label, multicenter, randomized, umbrella study in participants with locally advanced squamous cell carcinoma of the head and neck (SCCHN). The study will enroll treatment-naive participants with resectable Stage III-IVA human papillomavirus (HPV)-negative, programmed death-ligand 1 (PD-L1)-positive SCCHN with measurable disease, as assessed by the investigator according to Response Evaluation Criteria in Solid Tumors, Version 1.1 (RECIST v1.1) who have not received systemic treatment for their disease.

Squamous Cell Carcinoma of the Head and Neck

Hoffmann-La Roche12 participantsStarted Apr 2023

Duarte, California, United States • Philadelphia, Pennsylvania, United States • Pittsburgh, Pennsylvania, United States +3 more locations

DFC 004 Biomarkers for Active Diabetic Foot Ulcers

A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)

Find Trials by Condition in Pittsburgh

Safety Study of a Vaccine to Help Protect Against Lyme Disease in Healthy Children

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

Cross-Seal Closure Device IDE Trial - Study of the Cross-SealTM Suture-Mediated Vascular Closure Device System

Study of Anti-Malarials in Incomplete Lupus Erythematosus

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

BlueWind RENOVA iStim™ System for the Treatment of OAB

The Pediatric Artificial Pancreas Automated Initialization Trial

28-Day Study of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease

Study to Evaluate SAGE-547 Injection as Adjunctive Therapy for the Treatment of Super-Refractory Status Epilepticus

Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children

A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression

Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer

A Dose-Range Study of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Parkinson's Disease Mild Cognitive Impairment (PD-MCI)