Clinical Trials in Pittsburgh

Showing 2521-2540 of 18,076 trials

Muscle Impact of Treating Osteoporosis

NCT05666310

Osteosarcopenia is a geriatric musculoskeletal syndrome characterized by co-existence of osteoporosis and sarcopenia (low skeletal muscle mass, strength, and/or functional capacity). There is strong evidence of overlap between the pathophysiology of osteoporosis and sarcopenia (muscle-bone crosstalk). This research plan will further explore the relationship between bone and muscle, and provide new information about effect of osteoporosis medications on muscle health in older adults who are under treatment for osteoporosis.

SarcopeniaOsteoporosis

Nami Safai Haeri20 participantsStarted Feb 2023

Pittsburgh, Pennsylvania, United States

COMPLETEDNA< 1 mile

Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children

NCT05473767

This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on postpartum mothers and infants. The investigators will adapt a cardiovascular health intervention into an evidence-based home visiting program, Family Check-Up to create Family Check-Up Heart. Through a Type 1 hybrid effectiveness implementation design, the pilot study will test the feasibility and effectiveness of Family Check-Up Heart (Family Check-Up Heart, n=100; Family Check-Up, n=50). The investigators hypothesize that Family Check-Up Heart will show comparable levels of engagement and acceptability as Family Check-Up alone, and mothers receiving Family Check-Up Heart will have greater improvements in cardiovascular health at 6 months postpartum compared to Family Check-Up alone.

Obesity, MaternalHypertension in PregnancyHypertension, Pregnancy-Induced+2 more

University of Pittsburgh117 participantsStarted Nov 2022

Pittsburgh, Pennsylvania, United States • Pittsburgh, Pennsylvania, United States • Pittsburgh, Pennsylvania, United States

Muscle Impact of Treating Osteoporosis

Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children

Find Trials by Condition in Pittsburgh

Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases

A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

PREVENT ALL ALS Study

ASSESS ALL ALS Study

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic Cancer

Study of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1

IC-8 Apthera IOL New Enrollment Post Approval Study

Use of Sentinel Lymph Node Biopsy in Patients With Early-Stage, Palpable Node-Positive HR+/HER2- Breast Cancer Having Upfront Surgery and Adjuvant Radiation

A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Virtual Nephrologist

Randomized Withdrawal Study in Patients With Schizophrenia

RNS System LGS Feasibility Study

Antidepressant Effects of Nitrous Oxide

A Study to See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic Encephalopathy