Clinical Trials in Pittsburgh

Showing 20621-20640 of 21,047 trials

Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress

NCT00177892

The purpose of this study is to define the mechanism(s) through which Obstructive Sleep Apnea/Hypopnea (OSAH) promotes abnormal metabolic processes which characterize the metabolic syndrome. The investigators hypothesize that the sleep fragmentation and intermittent sleep hypoxia which occur in OSAH patients promote oxidative stress and inflammation which in turn lead to insulin resistance, dyslipidemia, abnormal vascular reactivity and other processes which are consistent with the metabolic syndrome.

Obstructive Sleep ApneaMetabolic Syndrome X

National Institute on Aging (NIA)76 participantsStarted Sep 2003

Pittsburgh, Pennsylvania, United States

TERMINATEDPhase 3< 1 mile

A Clinical Trial Assessing the Impact of Inhaled Insulin on Glucose Disposition

NCT00287066

To assess the impact of inhalation of insulin on glucose disposition in patients with type 1 diabetes

Diabetes Mellitus

Pfizer22 participantsStarted Feb 2006

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Huperzine A in Alzheimer's Disease

NCT00083590

The present study will evaluate the safety and efficacy of the Chinese herb huperzine A in the treatment of Alzheimer's disease (AD) in a randomized controlled trial of its effect on cognitive function.

Alzheimer Disease

National Institute on Aging (NIA)150 participantsStarted Apr 2004

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Irvine, California, United States +26 more locations

Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress

A Clinical Trial Assessing the Impact of Inhaled Insulin on Glucose Disposition

Huperzine A in Alzheimer's Disease

Find Trials by Condition in Pittsburgh

Phase I Trial of Silymarin for Chronic Liver Diseases

Study to Estimate the Effects of Inhaled Versus Intravenous (IV) Infusion of Human Insulin in Subjects With Type 1 Diabetes

PET Imaging of Regional Variation in Insulin Sensitivity of Adipose Tissue in Humans

Effect of Patient-Centered Care (PCC) on Patient Satisfaction at Hospital Discharge

Testing the Nocturnal Sleep Latency Profile in Primary Insomnia

Pharmacogenomics Blood Sampling Protocol For Irinotecan/Fluorouracil/Leucovorin(CPT-11/FU/LV).

Study of NGX-4010 for the Treatment of Painful HIV-Associated Neuropathy

A Multi-Centered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 (Zuragen) Solution, and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis

The Atrial High Rate Episodes in Pacemaker Patients

Safety and Efficacy Study of AV608 in Subjects With Social Anxiety Disorder

A Preliminary Clinical Study to Evaluate Fispemifene in the Treatment of Hypogonadism

Study of ONTAK (Denileukin Diftitox) in Previously Treated Cutaneous T-Cell Lymphoma Patients

NGX-4010 for the Treatment of Postherpetic Neuralgia

Effectiveness Study of Vilazodone to Treat Depression and to Discover Genetic Markers Associated With Response

ProStat Supplementation in Dialysis Patients

A Safety, Tolerability and Efficacy Study of E7070 in Patients With Renal Cell Carcinoma

PHIRST-1: Tadalafil in the Treatment of Pulmonary Arterial Hypertension