Clinical Trials in Phoenix

Showing 8121-8140 of 16,646 trials

OCS Lung Expand Post-Approval Study - Expand Follow-Up Data Collection

NCT04194398

Collection of five year follow-up data on patients who have already participated in the EXPAND Lung trial and have had transplants with donor lungs preserved on the OCS Lung System.

OCS Lung System

TransMedics79 participantsStarted Dec 2018

Phoenix, Arizona, United States • Los Angeles, California, United States • San Francisco, California, United States +5 more locations

COMPLETEDPhase 3< 1 mile

Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine

NCT02842853

The purpose of the study was to evaluate immune lot consistency of Meningococcal Polysaccharide (Serogroups A, C, Y and W) Tetanus Toxoid (MenACYW) Conjugate vaccine and the immune non-inferiority compared to the licensed vaccine Menactra®, and describe the safety and additional immunogenicity of these study vaccines in adolescents and adults 10 to 55 years of age in the United States (US). Primary Objectives: * To demonstrate the immune lot consistency of the antibody responses to meningococcal serogroups A, C, Y, and W following the administration of a single dose of MenACYW Conjugate vaccine with respect to serum bactericidal assay using human complement (hSBA) geometric mean titers (GMTs). * To demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C, Y, and W following the administration of a single dose of MenACYW Conjugate vaccine (pooled Lots 1 to 3) compared to those observed following the administration of a single dose of Menactra®. Secondary Objective: * To demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C, Y, and W following the administration of a single dose of MenACYW Conjugate vaccine (pooled Lots 1 to 3) compared to those observed following the administration of a single dose of Menactra® in the adult population (18 to 55 years old). * To demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C, Y, and W following the administration of a single dose of MenACYW Conjugate vaccine (pooled Lots 1 to 3) compared to those observed following the administration of a single dose of Menactra® in the adolescent population (10 to 17 years old). * To compare the hSBA vaccine seroresponses of meningococcal serogroups A, C, Y, and W for each of 3 lots of MenACYW Conjugate vaccine 30 days (+14 days) after vaccination. * To compare the hSBA antibody GMTs of meningococcal serogroups A, C, Y, and W following the administration of MenACYW Conjugate vaccine to those observed following the administration of Menactra®. Observational Objectives: * To describe the safety profile of MenACYW Conjugate vaccine and that of the licensed Menactra®.

MeningitisMeningococcal MeningitisMeningococcal Infections

Sanofi Pasteur, a Sanofi Company3,344 participantsStarted Jul 2016

Birmingham, Alabama, United States • Dothan, Alabama, United States • Mobile, Alabama, United States +86 more locations

OCS Lung Expand Post-Approval Study - Expand Follow-Up Data Collection

Immune Lot Consistency, Immunogenicity, and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine

Find Trials by Condition in Phoenix

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Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults

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Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Adults 56 Years and Older

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A Study of Oral Contraception Under Simulated OTC Conditions

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Safety and Immunogenicity of Different Dosages of High-Dose Quadrivalent Influenza Vaccine in Children 6 Months to 17 Years of Age

Reducing Involuntary Movements in Participants With Tardive Dyskinesia

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Levothyroxine Sodium in Thyroidectomized Patients Taking Proton Pump Inhibitors

Immunogenicity, Safety, Reactogenicity, Efficacy, Effectiveness and Lot Consistency of FluBlok

Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy

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QuikClot Control+ Hemostatic Dressing Use in Mild to Moderate Bleeding

Benign Liver Optimal Core Study (Tissue Acquisition Comparison in Benign Liver Disease)