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Clinical Trials in Philadelphia | 20,904 Studies Near You | Clareo Health

Clinical Trials LocationsPhiladelphia

Clinical Trials in Philadelphia

Discover 20,904 clinical trials near Philadelphia, Pennsylvania. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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Showing 18961-18980 of 20,904 trials

COMPLETEDNA< 1 mile

Comparing Use of the Glidescope Cobalt to Direct Laryngoscopy in Infants

NCT01163656

The investigators seek to prospectively compare intubation with the Glidescope Cobalt to Direct Laryngoscopy (DL) in infants.

Children's Hospital of Philadelphia66 participantsStarted Jul 2010

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

Open Label Continuation Study in Moderate to Severe Psoriasis

NCT00626002

The purpose of this study is to evaluate long term safety, efficacy and tolerability of ABT-874 in adults with moderate to severe psoriasis.

Moderate to Severe Plaque Psoriasis

AbbVie (prior sponsor, Abbott)2,301 participantsStarted Feb 2008

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Huntsville, Alabama, United States +149 more locations

Find Trials by Condition in Philadelphia

Breast Cancerin Philadelphia Lung Cancerin Philadelphia Prostate Cancerin Philadelphia Colorectal Cancerin Philadelphia Melanomain Philadelphia Leukemiain Philadelphia Lymphomain Philadelphia Pancreatic Cancerin Philadelphia Ovarian Cancerin Philadelphia Brain Cancerin Philadelphia

Data from ClinicalTrials.govTerms

COMPLETEDPhase 3< 1 mile

Computer-Based Survey and Communication Aid in Improving Physician-Patient Communication and Treatment Decision Making in Patients With Metastatic Cancer

NCT00244868

RATIONALE: A computer-based survey and communication aid may help physicians and patients to communicate better and help make treatment decisions easier. PURPOSE: This phase III randomized clinical trial is studying how well giving a computer-based survey together with a communication aid works compared to a computer-based survey alone in improving physician-patient communication and treatment decision making in patients with metastatic cancer.

Metastatic CancerUnspecified Adult Solid Tumor, Protocol Specific

Fox Chase Cancer Center720 participantsStarted Jul 2003

Chicago, Illinois, United States • Philadelphia, Pennsylvania, United States • Nashville, Tennessee, United States

COMPLETEDPhase 1< 1 mile

BMS-214662 Plus Trastuzumab in Treating Patients With Advanced Solid Tumors

NCT00022529

Phase I trial to study the effectiveness of BMS-214662 plus trastuzumab in treating patients who have advanced solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may kill more tumor cells

Unspecified Adult Solid Tumor, Protocol Specific

National Cancer Institute (NCI)28 participantsStarted Jul 2001

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 1< 1 mile

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

NCT00028496

Phase I trial to study the effectiveness of vaccine therapy with or without sargramostim in treating patients who have advanced or metastatic cancer. Vaccines may make the body build an immune response to kill tumor cells. Colony-stimulating factors such as sargramostim may increase the number of immune cells found in bone marrow or peripheral blood. Combining vaccine therapy with sargramostim may make tumor cells more sensitive to the vaccine and may kill more tumor cells

Adenocarcinoma of the ColonAdenocarcinoma of the GallbladderAdenocarcinoma of the Pancreas+39 more

National Cancer Institute (NCI)48 participantsStarted Nov 2001

Philadelphia, Pennsylvania, United States

COMPLETED< 1 mile

Variability of Ventricular Mass, Volume, & Ejection Fraction in Pediatric Cardiomyopathy Patients-Pediatric Heart Network

NCT00123071

This observational study will provide data (variations in ventricular size and function) that are essential to designing and conducting clinical trials. In addition, the study will evaluate intra- and inter-study variability seen in echocardiography.

Cardiomyopathy, Dilated

Carelon Research131 participantsStarted May 2005

Boston, Massachusetts, United States • St Louis, Missouri, United States • New York, New York, United States +5 more locations

COMPLETEDPhase 1< 1 mile

17-N-Allylamino-17-Demethoxygeldanamycin and Paclitaxel in Treating Patients With Metastatic or Unresectable Solid Tumor

NCT00087217

This phase I trial is studying the side effects and best dose of 17-N-allylamino-17-demethoxygeldanamycin when given together with paclitaxel in treating patients with metastatic or unresectable solid tumor. Drugs used in chemotherapy, such as 17-N-allylamino-17-demethoxygeldanamycin and paclitaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining 17-N-allylamino-17-demethoxygeldanamycin with paclitaxel may kill more tumor cells

Unspecified Adult Solid Tumor, Protocol Specific

National Cancer Institute (NCI)35 participantsStarted May 2004

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Thalidomide in Treating Patients With Recurrent or Persistent Endometrial Cancer

NCT00025467

Phase II trial to study the effectiveness of thalidomide in treating patients who have recurrent or persistent endometrial cancer. Thalidomide may stop the growth of cancer by stopping blood flow to the tumor

Endometrial AdenoacanthomaEndometrial AdenocarcinomaEndometrial Adenosquamous Cell Carcinoma+3 more

National Cancer Institute (NCI)60 participantsStarted Sep 2001

Philadelphia, Pennsylvania, United States

WITHDRAWNPhase 313 miles

A Phase 3 Study of Siltuximab or Placebo in Combination With Velcade and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

NCT01266811

The purpose of this study is to determine if there is an improvement in progression-free survival (length of time during and after treatment in which a patient is living with a disease that does not get worse) when siltuximab is added to VELCADE and dexamethasone in subjects with relapsed or refractory multiple myeloma.

Multiple Myeloma

Centocor, Inc.Started Jul 2011

Iowa City, Iowa, United States • Boston, Massachusetts, United States • Toledo, Ohio, United States +45 more locations

COMPLETEDPhase 314 miles

Trial of Linaclotide in Patients With Chronic Constipation

NCT00730015

The objective of this trial is to determine the efficacy and safety of linaclotide administered to patients with chronic constipation (CC). The primary efficacy parameter is the percentage of patients in each dosing group that meet the protocol definition for Complete Spontaneous Bowel Movement (CSBM) Overall Responder.

Chronic Constipation

Ironwood Pharmaceuticals, Inc.643 participantsStarted Aug 2008

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Chandler, Arizona, United States +102 more locations

COMPLETEDPhase 336 miles

S0012 Doxorubicin, Cyclophosphamide, and Paclitaxel With or Without Filgrastim in Treating Women With Inflammatory or Locally Advanced Breast Cancer

NCT00016406

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether combination chemotherapy is more effective with or without filgrastim in treating breast cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of combining doxorubicin, cyclophosphamide, and paclitaxel with or without filgrastim in treating women who have inflammatory or locally advanced breast cancer.

SWOG Cancer Research Network399 participantsStarted May 2001

Mobile, Alabama, United States • Anchorage, Alaska, United States • Fairbanks, Alaska, United States +311 more locations

COMPLETEDPhase 280 miles

S9911, Combination Chemotherapy Plus Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma

NCT00003784

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. Monoclonal antibodies can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by monoclonal antibody therapy in treating patients who have newly diagnosed follicular non-Hodgkin's lymphoma.

SWOG Cancer Research Network102 participantsStarted May 1999

Mobile, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +84 more locations

COMPLETEDPhase 281 miles

S0121, Neoadjuvant Carboplatin, Paclitaxel, and Gemcitabine Followed by Cisplatin and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Carcinoma of the Urothelium

NCT00055835

RATIONALE: Drugs used in chemotherapy, such as carboplatin, paclitaxel, gemcitabine, and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Giving chemotherapy before radiation therapy, and combining chemotherapy with radiation therapy, may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of neoadjuvant gemcitabine, paclitaxel, and carboplatin followed by cisplatin and radiation therapy in treating patients who have locally advanced or recurrent carcinoma (cancer) of the urothelium.

Bladder CancerUrethral Cancer

SWOG Cancer Research Network7 participantsStarted Nov 2002

Mobile, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +89 more locations

WITHDRAWNPhase 381 miles

FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

NCT00760916

This study is an international, multi-center, randomized, double-blind, placebo-controlled study in subjects with PAH who are currently receiving approved therapy for their PAH (i.e., endothelin receptor antagonist and/or phosphodiesterase-5 inhibitor)or as a monotherapy treatment. Study visits will occur at 4 week intervals for 12 weeks with the key measure of efficacy being the 6-minute walk test. Study procedures include routine blood tests, medical history, physical exams, disease evaluation, and exercise tests. At the end of the first 12-weeks, the patient will be un-blinded. Patients will continue with another 12-Week open label portion with visits occuring at 4-week intervals. Patients who complete all assessments for 24-weeks will also be eligible to enter a 36 month open-label, extension phase study (FREEDOM - EXT).

Pulmonary Hypertension

United TherapeuticsStarted Dec 2008

Birmingham, Alabama, United States • Los Angeles, California, United States • Sacramento, California, United States +28 more locations

COMPLETEDPhase 281 miles

S0102: Docetaxel, Vinorelbine, and Filgrastim in Treating Women With Stage IV Breast Cancer

NCT00015938

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of combining docetaxel, vinorelbine, and filgrastim in treating women who have stage IV breast cancer.

SWOG Cancer Research Network95 participantsStarted May 2001

Mobile, Alabama, United States • Anchorage, Alaska, United States • Phoenix, Arizona, United States +96 more locations

COMPLETEDNA87 miles

Treatment of Androgenic Alopecia in Males

NCT00947219

The purpose of this study is to evaluate the change in terminal hair count at 16 and 26 weeks compared to baseline measurements.

Androgenetic AlopeciaHair LossMale Pattern Baldness

Lexington International, LLC79 participantsStarted Jul 2009

West Palm Beach, Florida, United States • Hackensack, New Jersey, United States • High Point, North Carolina, United States

TERMINATEDNA119 miles

Optimize RV Selective Site Pacing Clinical Trial

NCT00422669

The purpose of the Optimize RV study is to determine the long-term effect of selective site pacing. Selective site pacing refers to which area of the right ventricle the lead is placed. The goal of select site pacing is to improve how the heart contracts when paced in the ventricle. By pacing in select sites, it is possible to better copy the natural pattern of contraction of the heart.

Cardiac Pacing, ArtificialCardiac Pacemaker, Artificial

Medtronic Cardiac Rhythm and Heart Failure205 participantsStarted Jan 2007

Bridgeport, Connecticut, United States • Clearwater, Florida, United States • Hudson, Florida, United States +19 more locations

COMPLETEDNA161 miles

Pediatric Nasal Mask Usability Study

NCT01154322

The purpose of the study is to demonstrate the effectiveness of a pediatric mask in treating obstructive sleep apnea (OSA) in a pediatric population.

Obstructive Sleep Apnea

ResMed16 participantsStarted Jun 2010

Redwood City, California, United States • Aurora, Colorado, United States • Wallingford, Connecticut, United States

COMPLETEDPhase 3332 miles

A Study of Safety and Efficacy Comparing ABT-874 Versus Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis

NCT00679731

This study is being conducted to compare the efficacy of ABT-874 versus Methotrexate in subjects with moderate to severe plaque psoriasis.

AbbVie (prior sponsor, Abbott)317 participantsStarted Apr 2008

Graz, Austria • Vienna, Austria • Vienna, Austria +40 more locations

COMPLETEDPhase 2358 miles

Study Evaluating SKI-606 (Bosutinib) In Subjects With Breast Cancer

NCT00319254

The purpose of this study is to determine if SKI-606 (Bosutinib) is effective in the treatment of advanced or metastatic breast cancer. Patients must have current Stage IIIB, IIIC or IV breast cancer and have progressed after 1 to 3 prior chemotherapy regimens.

Breast NeoplasmsNeoplasm Metastasis

Pfizer75 participantsStarted May 2006

Duarte, California, United States • Santa Monica, California, United States • Tampa, Florida, United States +12 more locations

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