Clinical Trials in Philadelphia

Showing 14461-14480 of 20,904 trials

A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer

NCT00398567

The purpose of this study is to determine the safety and efficacy of HKI-272 (neratinib) in combination with trastuzumab in patients with advanced breast cancer.

Advanced Breast Cancer

Puma Biotechnology, Inc.45 participantsStarted Apr 2007

Duarte, California, United States • Los Angeles, California, United States • Pasadena, California, United States +11 more locations

COMPLETEDPhase 3< 1 mile

Open Label Study of Long Term Safety Evaluation of Alirocumab

NCT01954394

Primary Objective: To assess the long-term safety of alirocumab (SAR236553/REGN727) when added to lipid-lowering therapy in participants with heterozygous familial hypercholesterolemia (heFH) who had completed EFC12492 (NCT01623115), R727-CL-1112 (NCT01709500), EFC12732 (NCT01617655) and LTS11717 (NCT01507831). Secondary Objectives: * To evaluate the long-term efficacy of alirocumab on lipid parameters. * To evaluate the long-term immunogenicity of alirocumab.

Hypercholesterolemia

Sanofi986 participantsStarted Dec 2013

Huntsville, Alabama, United States • Tempe, Arizona, United States • Bell Gardens, California, United States +174 more locations

A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer

Open Label Study of Long Term Safety Evaluation of Alirocumab

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Neural Injury in Adolescents With Concussion

Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps

Evaluation of Safety and Immunogenicity of Co-administering HPV Vaccine With Other Vaccines in Healthy Female Subjects

Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset Seizures

Trial to Assess Long-term Lacosamide (LCM) Monotherapy Use and Safety of LCM Monotherapy and Adjunctive Therapy for Partial-onset Seizures

Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo

A Study of LY2409021 on Blood Pressure and Pulse Rate in Participants With Type 2 Diabetes Mellitus

A Prospective Study in Patients Undergoing Primary Ventral Hernia Repair Using Parietex™ Composite Ventral Patch

Pegylated Interferon Alpha-2b in Early Primary Myelofibrosis

Evaluating How the Treatments in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study Affect Diabetic Retinopathy (The ACCORD Eye Study)

Phase II Safety Study of Vemurafenib Followed by Ipilimumab in Subjects With V600 BRAF Mutated Advanced Melanoma

Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients

Clinical Evaluation of Approved and Investigational Contact Lenses Using New UV Additive

A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With Phosphatase and Tensin Homolog (PTEN) Deficiency

Efficacy And Safety Of CX516 In Elderly Participants With Mild Cognitive Impairment.

Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis