Clinical Trials in Philadelphia

Showing 14201-14220 of 20,904 trials

LC Bead Embolization Agent With Doxorubicin in the Treatment Liver Metastasis From Melanoma

NCT01010984

The purpose of this study is to determine if LC beads loaded with Doxorubicin are a safe and effective treatment for melanoma that has spread to the liver.

Stage IV Melanoma

Robert C. Martin20 participantsStarted Sep 2009

Louisville, Kentucky, United States • Philadelphia, Pennsylvania, United States • Houston, Texas, United States

TERMINATEDPhase 1/2< 1 mile

Lenalidomide and Low-Dose Dexamethasone in Patients With Previously Treated Multiple Myeloma and Kidney Dysfunction

NCT00790842

Patients with previously treated multiple myeloma and kidney dysfunction will be treated with lenalidomide and low-dose dexamethasone. Phase I will study the side effects and best dose of lenalidomide when given together with low-dose dexamethasone therapy. After the maximum safe and tolerated dose is found in Phase I, the study will proceed to Phase II. Phase II will study how well the the treatment works in patients with previously treated (relapsed or refractory) multiple myeloma and kidney dysfunction. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving lenalidomide together with dexamethasone may kill more cancer cells. Lenalidomide and dexamethasone may have different effects in patients who have changes in their kidney function.

Multiple MyelomaPlasma Cell Neoplasm

PrECOG, LLC.63 participantsStarted Jan 2009

Scottsdale, Arizona, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +13 more locations

LC Bead Embolization Agent With Doxorubicin in the Treatment Liver Metastasis From Melanoma

Lenalidomide and Low-Dose Dexamethasone in Patients With Previously Treated Multiple Myeloma and Kidney Dysfunction

Find Trials by Condition in Philadelphia

PEDS-C: Pegylated Interferon +/- Ribavirin for Children With Hepatitis C

Trinity Evolution in Posterior or Transforaminal Lumbar Interbody Fusion (PLIF/TLIF)

BKM120 for Patients With PI3K-activated Tumors

Long-term Open-Label Safety Study to Evaluate EN3409

Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer

Safety and Efficacy of OMS643762 in Subjects With Huntington's Disease

Knee Arthroplasty Pain Coping Skills Training (KASTPain): A Randomized Trial

A Study of CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites

Efficacy and Safety Study of Cinacalcet for the Treatment of Hypercalcemia in Patients With Primary Hyperparathyroidism Unable to Undergo Parathyroidectomy

Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis

CHESS: Human and Computer Mentors for Prostate Cancer Patients

Phase 3 Study of M923 and Humira® in Subjects With Chronic Plaque-type Psoriasis

Safety and Immunogenicity of Different Dosing Schedules of GlaxoSmithkline (GSK) Biologicals' Herpes Zoster (HZ) Vaccine in Adults 50 Years of Age or Older

A Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer

A Dose Finding and Expansion Study of RO7051790 Administered Orally in Participants With Relapsed, Extensive-Stage Disease Small Cell Lung Cancer (ED SCLC)

Pharmacodynamics and Pharmacokinetics Study of Existing DMPA Contraceptive Methods

Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety