Clinical Trials in Philadelphia

Showing 1321-1340 of 17,926 trials

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

NCT06256484

The purpose of this study is to evaluate the safety and preliminary efficacy of ATA3219 in participants with relapsed/refractory (R/R) B-cell non-Hodgkin Lymphoma (NHL).

Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Atara Biotherapeutics1 participantsStarted Sep 2024

Orlando, Florida, United States • Louisville, Kentucky, United States • Philadelphia, Pennsylvania, United States +3 more locations

TERMINATEDPhase 1< 1 mile

Next Generation Personalized Neuroblastoma Therapy

NCT02780128

The purpose of this research study is to match genomic aberrations in tumor cells at time of relapse to rationally designed combinations of molecularly targeted agents. This study will be done in two parts: Part I: Tumor will be accessed at study entry via a biopsy and subjected to deep sequencing to identify protocol-specified biomarkers for therapy assignment. Part II: If the tumor contains a genetic change defined by the study as being actionable, and other criteria are met, participants will be assigned to therapy based upon the genetic changes identified in the tumor biopsy.

NeuroblastomaCancer

Yael P Mosse66 participantsStarted Jul 2016

Philadelphia, Pennsylvania, United States

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Next Generation Personalized Neuroblastoma Therapy

Find Trials by Condition in Philadelphia

A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors

BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy

Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

A Global Prospective Observational Registry of Patients With Pompe Disease

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

Uterine Leiomyoma Treatment With Radiofrequency Ablation (ULTRA) Registry

Dose Optimization and Expansion Study of DFV890 in Adult Patients With Myeloid Diseases

A Study to Investigate the Efficacy and Safety of Volrustomig ± Casdatifan vs Nivolumab + Ipilimumab as 1L Treatment for Advanced ccRCC

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Study to Evaluate the Safety, Tolerability, PDs, and Efficacy of CNP-104 in Subjects With Primary Biliary Cholangitis

Phase 1-2 Study of Low Dose ASTX727 (ASTX727 LD) in Lower Risk MDS

OsteoGen Plug vs. Freeze-dried Bone Allograft With Collagen Barrier

Efficacy and Safety of Tildrakizumab Compared to Placebo in Anti-TNF naïve Subjects With Active Psoriatic Arthritis II (INSPIRE 2)

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment