Clinical Trials in Philadelphia

Showing 11541-11560 of 20,904 trials

Interferon Gamma-1b in Friedreich Ataxia (FRDA)

NCT01965327

Friedreich ataxia (FRDA) is a progressive neurodegenerative disease of children and adults for which there is presently no therapy. Recently, a study reported that interferon gamma (IFN-g) could raise frataxin protein levels in both cell lines derived from patients with Friedreich ataxia and in a mouse model with Friedreich ataxia. The present study will test whether IFN-g is safe, tolerated and potentially efficacious in a heterogeneous cohort of children with FRDA.

Friedreich Ataxia

Children's Hospital of Philadelphia12 participantsStarted Aug 2013

Philadelphia, Pennsylvania, United States

COMPLETED< 1 mile

Study of Pediatric Migraine: The Pediatric Migraine Registry

NCT03742024

This is a multi-center registry that will prospectively collect regulatory compliant data from children and adolescents with migraine. This study will enroll approximately 200 participants from approximately 20 sites and will examine migraine symptoms, therapeutics used, and biomarkers associated with migraine.

Migraine

Duke University201 participantsStarted Dec 2018

San Francisco, California, United States • Colorado Springs, Colorado, United States • Wilmington, Delaware, United States +16 more locations

Interferon Gamma-1b in Friedreich Ataxia (FRDA)

Study of Pediatric Migraine: The Pediatric Migraine Registry

Find Trials by Condition in Philadelphia

A Safety, Efficacy and Pharmacokinetics Study of CD11301 for the Treatment of Cutaneous T-Cell Lymphoma (CTCL)

Depression Prevention Initiative - A Study of Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) in School Settings

Rheos System for the Treatment of HFpEF Heart Failure

A Study of ALKS 5461 for Treatment Refractory Major Depressive Disorder (MDD)

eHealth Weight Loss Program in African American Breast Cancer Survivors

Cytoreductive Prostatectomy in Treating Patients With Newly Diagnosed, Metastatic Prostate Cancer

Focus Group in Collecting Feedbacks From Indoor Tanning Bed Users for Social Media-Delivered Intervention Development

Collecting and Storing Blood and Tumor Tissue Samples From Patients Undergoing Prostatectomy or Transurethral Resection of the Prostate

Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners

Phase Ib Trial of LEE011 With Everolimus (RAD001) and Exemestane in the Treatment of Hormone Receptor Positive HER2 Negative Advanced Breast Cancer

A Phase II Study of M2951 in SLE

A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of Insomnia

Refametinib(BAY86-9766) in RAS Mutant Hepatocellular Carcinoma (HCC)

A Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function

A Clinical Study to Evaluate the Effect of the Connected Inhaler System (CIS) on Adherence to Maintenance Therapy in Poorly Controlled Asthmatic Subjects

Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 When Given Together With Chemotherapy and the Effectiveness of This Combination Treatment in Shrinking a Specific Type of Lung Tumors (Small Cell Lung Cancer)

Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC)

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors