Clinical Trials in Philadelphia

Showing 11261-11280 of 20,904 trials

Testing AZD4547 as a Potential Targeted Treatment in Cancers With FGFR Genetic Changes (MATCH-Subprotocol W)

NCT04439240

This phase II MATCH treatment trial identifies the effects of AZD4547 in patients whose cancer has genetic changes called FGFR gene alterations. AZD4547 may stop the growth of cancer cells by blocking FGFR proteins which may be needed for cell growth. Researchers hope to learn if AZD4547 will shrink this type of cancer or stop its growth.

Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more

National Cancer Institute (NCI)52 participantsStarted May 2016

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

NCT03204318

The purpose of this study is to determine the benefit and safety of relugolix 40 milligrams (mg) once daily, co-administered with low-dose estradiol (E2) and norethindrone acetate (NETA) compared with placebo for 24 weeks, on dysmenorrhea and on nonmenstrual pelvic pain.

Endometriosis Related Pain

Myovant Sciences GmbH638 participantsStarted Dec 2017

Dothan, Alabama, United States • Mesa, Arizona, United States • Scottsdale, Arizona, United States +120 more locations

Testing AZD4547 as a Potential Targeted Treatment in Cancers With FGFR Genetic Changes (MATCH-Subprotocol W)

SPIRIT 1: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

Find Trials by Condition in Philadelphia

Peg-Interferon Alpha 2b Combined With Two Intravenous Broadly HIV-1 Neutralizing Antibodies 3BNC117 and 10-1074 (BEAT-2)

Clobetasol Topical Oil for Children With Moderate to Severe Atopic Dermatitis

Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer

Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip

Long-Term Safety and Tolerability Study of NKTR-181 in Subjects With Chronic Low Back Pain or Chronic Non-Cancer Pain

ITI-007 for the Treatment of Agitation in Patients With Dementia, Including Alzheimer's Disease

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control

Safety and Efficacy of Bexagliflozin as Monotherapy in Patients With Type 2 Diabetes

Regimen Optimization Study

A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With Inhibitors

Non-Inferiority Study of the FRESCA Airbox Positive Airway Pressure System

Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis

Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)

Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis

Rectal Safety and Acceptability Study of Tenofovir 1% Gel

An Extension Study of the Safety and Anti-leukemic Effects of Imatinib Mesylate in Participants With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in Blast Crisis