Clinical Trials in Philadelphia

Showing 9801-9820 of 20,904 trials

A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies

NCT03241173

The purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01949 when given in combination with immune therapies in participants with advanced or metastatic malignancies.

Advanced Malignancies

Incyte Biosciences International Sàrl52 participantsStarted Oct 2017

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Los Angeles, California, United States +12 more locations

TERMINATEDPhase 2< 1 mile

Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease

NCT03124459

This is a multicenter, phase 2 study to evaluate the safety, tolerability, pharmacodynamics (PD), efficacy, and pharmacokinetics (PK) of ACE-083 in patients with Charcot-Marie-Tooth Disease Type 1 and Type X (CMT1 and CMTX), to be conducted in two parts. Part 1 is non-randomized, open-label, dose-escalation and Part 2 is randomized, double-blind, and placebo-controlled.

Charcot-Marie-Tooth Disease

Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA63 participantsStarted Jul 2017

Orange, California, United States • Aurora, Colorado, United States • Gainesville, Florida, United States +13 more locations

A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies

Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease

Find Trials by Condition in Philadelphia

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))

A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Treating IBD With Inulin

A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type Melanoma

An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesothelioma

Fibromyalgia Outcome Research Trial Evaluating Synergistic Suppression of HSV-1

A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration

Comparison of VT Ablation Outcomes Using Remote MAGNETIC Navigation Versus Manual Approach in a Low LVEF Population

Study of Dalantercept and Sorafenib in Patients With Advanced Hepatocellular Carcinoma

A Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa

Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

Natural History Study in Huntington Disease Gene Expansion Carriers (HDGECs) - SHIELD HD

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)