Clinical Trials in Philadelphia

Showing 5701-5720 of 20,904 trials

Low-Carbohydrate Normocaloric Diet in Patients With Head and Neck Carcinoma (HNC)

NCT02555176

This pilot clinical trial studies the effects of a low carbohydrate diet on tumor metabolism in patients with head and neck cancer. A low carbohydrate diet may reduce the metabolic activity of cancer cells and of surrounding supportive tissues. Studying samples of tissue and blood from patients with head and neck cancer in the laboratory before and after a low carbohydrate diet may help determine any changes in tumor metabolism.

Head and Neck Carcinoma

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University7 participantsStarted Dec 2016

Philadelphia, Pennsylvania, United States

RECRUITINGPhase 1< 1 mile

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

NCT06371417

This Phase 1b basket trial will investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity and preliminary efficacy of RAY121, a inhibitor of classical complement pathway, after multiple dose administration in patients with immunological diseases such as antiphospholipid syndrome (APS), bullous pemphigoid (BP), Behçet's Syndrome (BS), dermatomyositis (DM), immune-mediated necrotizing myopathy (IMNM) and immune thrombocytopenia (ITP).

Antiphospholipid Syndrome (APS)Bullous Pemphigoid (BP)Behçet's Syndrome (BS)+3 more

Chugai Pharmaceutical144 participantsStarted Aug 2024

Orange, California, United States • Baltimore, Maryland, United States • Lake Success, New York, United States +64 more locations

Low-Carbohydrate Normocaloric Diet in Patients With Head and Neck Carcinoma (HNC)

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Find Trials by Condition in Philadelphia

The STandard Versus ImAging SuBstrate Aided Ablation in Severe Left VEntricular Dysfunction VT.

A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)

A Second Intermediate-Size Expanded Access Protocol (EAP) for Pridopidine in People With Amyotrophic Lateral Sclerosis (Pridopidine EAP 2)

StimRouter Registry Clinical Protocol

SURPASS Impella 5.5 Study

A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer

Clinical Trial of Approaches to Prostate Cancer Surgery

Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation

PRimary Care Opioid Use Disorders Treatment (PROUD) Trial

Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy

Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults

A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males

Stopping Aminosalicylate Therapy in Inactive Crohn's Disease

A Retrospective Chart Review Study of Patients With Chronic Lung Allograft Dysfunction-Bronchiolitis Obliterans Syndrome (CLAD-BOS) Post Lung Transplantation

Digital Support Systems to Improve Child Health and Development in Peru