Clinical Trials in Philadelphia

Showing 3541-3560 of 20,904 trials

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

NCT04416568

This clinical trial is studying two immunotherapy drugs (nivolumab and ipilimumab) given together as a possible treatment for INI1-negative tumors.

Malignant Rhabdoid TumorRhabdoid Tumor of the KidneyEpithelioid Sarcoma+4 more

Dana-Farber Cancer Institute45 participantsStarted Aug 2020

San Francisco, California, United States • Atlanta, Georgia, United States • Atlanta, Georgia, United States +5 more locations

RECRUITINGPhase 3< 1 mile

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

NCT06216301

This study, known as LUNAR-2, aims to investigate the effectiveness and safety of using TTFields, delivered by the NovoTTF-200T device, concomitantly administered with pembrolizumab and platinum-based chemotherapy for patients with advanced non-small cell lung cancer that has spread to other parts of the body. The primary goals of the study are to assess overall survival and progression-free survival. Secondary objectives include analyzing outcomes based on the specific histology (subtype) of the lung cancer.

Metastatic Non-small Cell Lung Cancer

NovoCure GmbH734 participantsStarted Jul 2024

Birmingham, Alabama, United States • Goodyear, Arizona, United States • Fullerton, California, United States +87 more locations

Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

Find Trials by Condition in Philadelphia

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1)

A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease

A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors

A Mobile Health Intervention Among Hispanics

A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer

A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis

Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome

A Study in Participants With Obesity or Overweight With at Least One Weight-related Comorbidity

A Trial of Varenicline for E-cigarette Cessation

An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitory Antibodies to Factor VIII or IX

Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors