Clinical Trials in Philadelphia

Showing 2521-2540 of 17,926 trials

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

NCT05721326

The goal of this sequential study design is to increase genetic testing in those meeting national clinical guidelines. The main question it aims to answer is: which intervention is most effective in uptake of genetic testing for the target population? Participants will receive genetic testing and counseling that may initiate life-saving screenings.

Genetic Predisposition to DiseaseBreast Cancer FemaleOvarian Cancer+4 more

Abramson Cancer Center at Penn Medicine1,330 participantsStarted May 2023

Philadelphia, Pennsylvania, United States

TERMINATEDPhase 2< 1 mile

PHE885 CAR-T Therapy in Adult Participants With Relapsed and Refractory Multiple Myeloma

NCT05172596

This is a Phase II study to determine the efficacy and safety of PHE885, a BCMA-directed CAR-T cell therapy, manufactured with a new process. The CAR-T cell therapy will be investigated as a single agent in relapsed and refractory multiple myeloma

Multiple Myeloma

Novartis Pharmaceuticals146 participantsStarted Mar 2022

Palo Alto, California, United States • Atlanta, Georgia, United States • Boston, Massachusetts, United States +33 more locations

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

PHE885 CAR-T Therapy in Adult Participants With Relapsed and Refractory Multiple Myeloma

Find Trials by Condition in Philadelphia

Study to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodularis

Study of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid Tumors

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS).

A Study of Fluorescein Sodium in People Undergoing Vulvectomy for Extramammary Paget's Disease (EMPD)

A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)

Liver Cirrhosis Network Cohort Study

ALRN-6924 in Patients With Advanced Solid Tumors or Lymphomas

A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)

A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013)

RNS System LGS Feasibility Study

Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan.

Study of an Investigational Pentavalent Meningococcal ABCYW Vaccine in Adults and Adolescents

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Antidepressant Effects of Nitrous Oxide

Long-Term Clinical, Immunologic, and Virologic Profiles of Children Who Received Early Treatment for HIV

Study of QMF149 (150/80 µg) Compared With MF Twisthaler® (200 µg) in Patients With Asthma