Clinical Trials in Pennsylvania

Showing 16481-16500 of 19,675 trials

Clinical Investigation of Expanded Designs of a Multifocal IOL

NCT01714635

The purpose of this clinical trial is to evaluate the safety and effectiveness of the TECNIS Multifocal 1-Piece Intraocular Lens (IOLs), Models ZKB00 and ZLB00 which will each provide statistically better distance-corrected near visual acuity compared to the monofocal control lens. Complication and adverse event rates associated with each Multifocal IOL will be within the ISO SPE rate for posterior chamber IOLs.

Cataract

Abbott Medical Optics445 participantsStarted Nov 2012

Tucson, Arizona, United States • Rogers, Arkansas, United States • Bakersfield, California, United States +15 more locations

COMPLETEDPhase 340 miles

SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated Myeloma

NCT00002548

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Combining chemotherapy and radiation therapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and radiation therapy and kill more cancer cells. It is not yet known which treatment regimen is more effective for multiple myeloma. PURPOSE: Randomized phase III trial to compare the effectiveness of melphalan, total-body irradiation, and peripheral stem cell transplantation with that of combination chemotherapy in treating patients who have previously untreated multiple myeloma.

Multiple Myeloma

SWOG Cancer Research Network899 participantsStarted Jan 1994

Scottsdale, Arizona, United States • Denver, Colorado, United States • Tampa, Florida, United States +31 more locations

Clinical Investigation of Expanded Designs of a Multifocal IOL

SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated Myeloma

Find Trials by Condition in Pennsylvania

NVA237 BID Versus Placebo Twelve-week Efficacy Study

Study of Meloxicam Capsules to Treat Osteoarthritis Pain

Safety and Tolerability Study of Intravitreal VEGF-Trap Administration in Patients With Neovascular AMD

Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery

Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 1 to Less Than 6 Years Suffering From Allergic Rhinitis or Chronic Urticaria of Unknown Origin

Nesvacumab (REGN910/ SAR307746) and Aflibercept ("Ziv-aflibercept" in the U.S.) in Patients With Advanced Solid Malignancies

A Multicenter Study to Evaluate the Effects of a 91-Day Extended Cycle Oral Contraceptive on Hemostatic Parameters in Healthy Women

A Study to Examine the Safety, Tolerability, and Body Weight Effect of Pramlintide Alone and in Combination With Oral Antiobesity Agents in Overweight and Obese Subjects

Identification and Validation of Biomarkers of Acute Kidney Injury Recovery

A Global Phase 3 Safety Study of 120 mcg rLP2086 Vaccine in Adolescents and Young Adults Aged 10 to 25 Years

Patient-Reported Outcomes in Adults With Congenital Heart Disease

TeleQuit Smoking Cessation Program

Phase 1 Dose Escalation Study of Autologous T-cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases in HIV-Infected Patients

Optimal Treatment for Kidney Disease in HIV Infected Adults

S9922 Combination Chemo Plus Filgrastim With or Without Thalidomide in Refractory Multiple Myeloma

Study of a New Medication for Childhood Chronic Immune Thrombocytopenia (ITP), a Blood Disorder of Low Platelet Counts That Can Lead to Bruising Easily, Bleeding Gums, and/or Bleeding Inside the Body.

Immediate Implant Placement in the Esthetic Zone

Fibroid Ablation Study - Large Fibroids