Clinical Trials in Pennsylvania

Showing 12661-12680 of 19,675 trials

Clofarabine, Etoposide, and Mitoxantrone for Relapsed and Refractory Acute Leukemias

NCT00882076

The purpose of this study is to establish toxicity and a maximum tolerated dose recommended phase 2 dose of Clofarabine in combination with Etoposide and Mitoxantrone for therapy of relapsed or refractory acute leukemias. The investigators will observe responses with these therapy agents and assess the impact of Clofarabine interacting with Etoposide in induction of DNA strand breaks.

Leukemia

Milton S. Hershey Medical Center22 participantsStarted Mar 2009

Hershey, Pennsylvania, United States

COMPLETEDPhase 365 miles

Extension in AS: Sustainability of Benefits, Safety and Tolerability

NCT01863732

This 3-year extension study aims at making available the treatment with secukinumab in prefilled syringes (PFS) to patients with ankylosing spondylitis who took part in phase III study CAIN457F2305, defined as "core study", as well as to generate additional data on the sustainability of clinical benefits, safety and tolerability during long-term administration of secukinumab.

Spondylitis, Ankylosing

Novartis Pharmaceuticals274 participantsStarted Nov 2013

Portland, Oregon, United States • Duncansville, Pennsylvania, United States • Jackson, Tennessee, United States +53 more locations

Clofarabine, Etoposide, and Mitoxantrone for Relapsed and Refractory Acute Leukemias

Extension in AS: Sustainability of Benefits, Safety and Tolerability

Find Trials by Condition in Pennsylvania

To Study Generic Tacrolimus Ointment, 0.1% in the Treatment of Moderate to Severe Atopic Dermatitis (Inflammation of Skin: Itchy, Red, Swollen, and Cracked Skin)

A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)

Long-term Study of Cariprazine in Patients With Schizophrenia

Safety and Efficacy of Relamorelin Administered to Participants With Vomiting Symptoms and Moderate to Severe Diabetic Gastroparesis

Down Syndrome Metabolic Health Study

Extended Varenicline Treatment for Smoking Among Cancer Patients

Treatment for Migraines With an Implantable Device

Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial

Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon

Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal Polyps

Study to Compare PT007 to Placebo MDI and Open-Label Proventil® HFA in Adult and Adolescent Subjects With Asthma

Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

Pharmacokinetics of Entospletinib in Adults With Normal and Impaired Liver Function

An Open-Label Extension Study Assessing the Long-Term Efficacy and Safety of ALX-0061 in Subjects With Rheumatoid Arthritis