Clinical Trials in Pennsylvania

Showing 5261-5280 of 19,675 trials

Flexiva Pulse Registry

NCT05027971

To obtain post-market safety and efficacy data for FlexivaTM Pulse High Power Single-Use Laser Fibers during lithotripsy and soft tissue procedure of holmium laser enucleation of the prostate (HoLEP).

Urinary CalculiBenign Prostatic Hyperplasia

Boston Scientific Corporation201 participantsStarted Nov 2021

Phoenix, Arizona, United States • Miami, Florida, United States • Orlando, Florida, United States +1 more locations

COMPLETEDPhase 393 miles

Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease

NCT04994483

A 52-week safety and efficacy study of simufilam (PTI-125) given twice daily to participants with mild-to-moderate Alzheimer's disease (AD) for 52 weeks. Approximately 750 participants will be randomized (1:1) to receive either placebo or 100 mg tablets of simufilam, twice daily, for 52 weeks. Clinic visits will occur 4 weeks after the baseline visit, and then every 12 weeks until the end of the study. The safety of simufilam, and its efficacy in enhancing cognition and slowing cognitive and functional decline will be evaluated.

Alzheimer Disease

Cassava Sciences, Inc.804 participantsStarted Nov 2021

Chandler, Arizona, United States • Gilbert, Arizona, United States • Phoenix, Arizona, United States +85 more locations

Flexiva Pulse Registry

Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease

Find Trials by Condition in Pennsylvania

SPIROMICS Study of Early COPD Progression (SOURCE)

A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis

Assessment of Safety and Effectiveness in Treatment Management of Atrial Fibrillation With the BWI IRE Ablation System

A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Impact of Hypothalamic Gliosis on Appetite Regulation and Obesity Risk in Children

A Study to Evaluate a Range of Dose Levels of an Adenovirus Serotype 26 (Ad26.RSV.preF)-Based Vaccine in Older Adults

An Open-Label Multiple Dose Study of RZ358 in Patients With Congenital Hyperinsulinism

Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

HEALing Communities Study

Compound 31543 (Calcitriol, USP) in Patients Receiving Taxane-based Chemotherapy Regimens for the Treatment of Chemotherapy-Induced Alopecia

Modifiers of Disease Severity in Cerebral Cavernous Malformations

RTA 402 in Patients With Advanced Solid Tumors or Lymphoid Malignancies

Safety and Tolerability of M254 in Healthy Volunteers and Immune Thrombocytopenic Purpura (ITP) Patients

A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

HbA1c Variation Study