Clinical Trials in Pennsylvania

Showing 4121-4140 of 19,675 trials

New Parent Support Program Evaluation

NCT05236192

The purpose of this study is to perform a program evaluation of the Navy and Marine Corps' New Parent Support Program (NPSP) home-visiting option. Both the Navy and Marine Corps have decided to pilot the Take Root Home Visitation (TRHV) curriculum, which is an evidence-informed, standardized program, with clients receiving NPSP home visits. This study is designed to examine the implementation and program effectiveness of TRHV compared to services as usual (SAU). Program outcomes include child development, parenting behaviors, child maltreatment risk and protective factors, and child maltreatment incidents. Implementation outcomes include clinicians' and clients' satisfaction with the program, clinicians' fidelity to the program delivery model, and clients' engagement with the program.

Child Maltreatment

Penn State University341 participantsStarted Feb 2023

University Park, Pennsylvania, United States

TERMINATEDPhase 353 miles

A Study of Xevinapant (Debio 1143) in Combination With Platinum-Based Chemotherapy and Standard Fractionation Intensity-Modulated Radiotherapy in Participants With Locally Advanced Squamous Cell Carcinoma of the Head and Neck, Suitable for Definitive Chemoradiotherapy (TrilynX)

NCT04459715

The primary objective of the study was to demonstrate superior efficacy of Xevinapant (Debio 1143) vs placebo when added to chemoradiotherapy (CRT) in locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN).

Squamous Cell Carcinoma of the Head and Neck

EMD Serono Research & Development Institute, Inc.730 participantsStarted Aug 2020

Birmingham, Alabama, United States • Gilbert, Arizona, United States • Tucson, Arizona, United States +285 more locations

New Parent Support Program Evaluation

A Study of Xevinapant (Debio 1143) in Combination With Platinum-Based Chemotherapy and Standard Fractionation Intensity-Modulated Radiotherapy in Participants With Locally Advanced Squamous Cell Carcinoma of the Head and Neck, Suitable for Definitive Chemoradiotherapy (TrilynX)

Find Trials by Condition in Pennsylvania

Futibatinib in Patients With Specific FGFR Aberrations

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females

A Clinical Trial of CAP-003 Gene Therapy in Adult Patients With GBA1 Associated Parkinson's Disease

Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD

Efficacy and Safety of Tisagenlecleucel in Adult Patients With Refractory or Relapsed Follicular Lymphoma

SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome

Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)

Cognitive Remediation for Coordinated Specialty Care

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)

Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation

Kaneka Endovascular Embolization and Protection

Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments

KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer

Study of Diagnostic Performance of [18F]CTT1057 for PSMA-positive Tumors Detection