Clinical Trials in Pennsylvania

Showing 2921-2940 of 16,895 trials

Prevention of Obesity in Infants of Overweight and Obese Women

NCT04782063

Maternal and childhood obesity have dramatically increased and continue to present a significant health problem. Studies show that offspring of overweight (body mass index, BMI \>25-29.9) and obese (BMI ≥30) women are at increased risk of newborn and age 1-year adiposity, and infant adiposity predicts childhood and adult obesity. The investigators hypothesize that infants of overweight/obese (OW/OB) mothers have both relative hyperphagia and are provided human milk with increased caloric composition, leading to obesity. The investigators propose an intervention study to calibrate milk or formula intake in infants of OW/OB mothers so as to avoid overweight infants at 6 months of age.

Infant Obesity

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center60 participantsStarted Jan 2022

Hershey, Pennsylvania, United States

COMPLETEDPhase 368 miles

Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)

NCT05813275

This is a Phase 3 Randomized Double-Blind Placebo-Controlled 6-month Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Obstructive Sleep Apnea.

OSA

Apnimed646 participantsStarted Sep 2023

Tuscaloosa, Alabama, United States • Mesa, Arizona, United States • Phoenix, Arizona, United States +70 more locations

Prevention of Obesity in Infants of Overweight and Obese Women

Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)

Find Trials by Condition in Pennsylvania

A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema

Study Comparing Emergency Contraception Effectiveness in Women Who Weight ≥ 80 kg

Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

Imaging Assessments of ARPKD Kidney Disease Progression

Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA)

Non-interventional Study on Osilodrostat in Patients With Endogenous Cushing's Syndrome

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation

Flexible-Dose Trial in Early Parkinson's Disease (PD)

A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain

A Study of HyQvia in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) in Routine Clinical Care

STENOVA - A Study to Evaluate Safety, Tolerability, PK and PD of AGMB-129 in Patients With Fibrostenotic Crohn's Disease