Clinical Trials in Pennsylvania

Showing 2481-2500 of 16,895 trials

Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas

NCT04869449

This research is being done to find out if the study drug (ketoconazole) can enter brain tumors at a high enough amount to stop the tumor cells from dividing. Ketoconazole is a drug which doctors already use for fungal infections and is thought to be able to effect tumor cells. As treatments for this type of brain tumor are limited, it is hoped that the results of this study will help to determine if the study drug should be studied further as a possible treatment.

GlioblastomaGlioblastoma MultiformeGlioblastoma Multiforme of Brain+1 more

Milton S. Hershey Medical Center1 participantsStarted May 2022

Hershey, Pennsylvania, United States

RECRUITING40 miles

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

NCT06174727

This multicenter retrospective cohort study aims to evaluate and compare the technical performance, safety, and clinical outcomes of intracranial aneurysms treated with flow diverter stents and endosaccular flow disruptors.

Intracranial Aneurysm

Montefiore Medical Center5,000 participantsStarted Oct 2023

Coral Gables, Florida, United States • Jacksonville, Florida, United States • Sarasota, Florida, United States +8 more locations

Active Not RecruitingPhase 371 miles

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

NCT05949593

This Phase 3, multicenter, double-masked, parallel-group, placebo-controlled, randomized, fixed-dose clinical study is designed to evaluate the efficacy and safety of tinlarebant (LBS-008) in subjects diagnosed with GA.

Geographic Atrophy

Belite Bio, Inc429 participantsStarted Jul 2023

Phoenix, Arizona, United States • Arcadia, California, United States • Beverly Hills, California, United States +46 more locations

Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas

International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Geographic Atrophy

Find Trials by Condition in Pennsylvania

Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies

Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH)

SEEG-Guided DBS for OCD

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

Conservative Surgery in Treating Patients With Low-Risk Stage IA2 or IB1 Cervical Cancer

A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Acupuncture for Chronic Low Back Pain in Older Adults

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Adults With Solid Malignancies

AB154 Combined With AB122 for Recurrent Glioblastoma

Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma

DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.