Clinical Trials in Ohio

Showing 16021-16040 of 20,938 trials

The Prevalence of Sleep Disordered Breathing in Hospitalized Patients With Acutely Decompensated Heart Failure Syndrome

NCT00701519

OSA is associated with large negative swings in the intrathoracic pressure, significant increase in the sympathetic nerve activity and repetitive surges in blood pressure, along with episodic hypoxia and hypercapnea (8,9). These autonomic and respiratory changes may increase the cardiac muscle workload, cardiac dysrrhythmia, and exacerbate ischemia (10,11,12). Treatment with CPAP is the most successful therapeutic modality available for OSA. It is still not clear whether establishing the diagnosis of OSA and initiating treatment with CPAP while still in the hospital carries any benefit in the management of patients with acute heart failure. This study will evaluate the effect of work up and treatment of OSA on the outcome of patients hospitalized with acute CHF.

Sleep ApneaCongestive Heart FailureHeart Failure

Ohio State University1,600 participantsStarted Jun 2007

Columbus, Ohio, United States

COMPLETEDNA32 miles

Corneal Biomechanics With Hydration in Normal and LASIK Eyes

NCT01183702

The research will utilize LASIK and non-LASIK populations to analyze the biomechanical differences between these corneas.

Laser Corneal Surgery

Deb Grzybowski44 participantsStarted Feb 2004

Columbus, Ohio, United States

COMPLETEDPhase 281 miles

Use Of SB424323 With Aspirin In Non-Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For Stroke

NCT00240643

This study will allow determination of the pharmacokinetic and pharmacodynamics of SB424323 in a relevant population. The data from this study will be used along with other data to aid in choosing the most appropriate dose for the later phase study.

Fibrillation, AtrialAtrial Fibrillation

GlaxoSmithKline640 participantsStarted Nov 2005

Mobile, Alabama, United States • Troy, Michigan, United States • Akron, Ohio, United States +113 more locations

The Prevalence of Sleep Disordered Breathing in Hospitalized Patients With Acutely Decompensated Heart Failure Syndrome

Corneal Biomechanics With Hydration in Normal and LASIK Eyes

Use Of SB424323 With Aspirin In Non-Valvular Atrial Fibrillation In Patients At A Low Or Intermediate Risk For Stroke

Find Trials by Condition in Ohio

Reserpine for the Treatment of Cocaine Dependence - 1

A Study To Evaluate The Safety And Tolerability Of PF-06342674 (RN168) In Subjects With Multiple Sclerosis (MS)

Use of Activated Recombinant Human Factor VII in Cardiac Surgery

HIV/STD Safer Sex Skills Groups for Men in Drug Treatment Programs - 1

A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne - W0260-301

Trial of NovoSeven® in Haemophilia - Joint Bleeds

Modafinil for the Treatment of Cocaine Dependence - 1

Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia

Percutaneous Cryoablation in Treating Patients With Painful Bone Metastases

Use of Activated Recombinant FVII in Spinal Surgery

Efficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) as Maintenance Treatment in Adults With Schizophrenia

Baclofen for the Treatment of Cocaine Dependence - 1

Motivational Incentives for Enhanced Drug Abuse Recovery: Methadone Clinics. - 1

Efficacy of NicVAX in Smokers Who Want to Quit Smoking

Motivational Interviewing to Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse - 1

A Trial of Extracorporeal Photopheresis, Pentostatin, and Total Body Irradiation in Patients Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation for the Treatment of Malignancies

Follow-up Study to Assess Visual Function in Subset of Patients Who Have Previously Participated in the TG-MV-006 and TG-MV-007 Ocriplasmin Studies