Clinical Trials in Ohio

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Peroneal and Achilles Tendon Repair Indications With CLARIX® CORD 1K

NCT02719288

Peroneal and Achilles tendon tears are common diseases that present challenges to surgeons due to tendon adhesion complications. Functional recovery is compromised by limiting post-operative range of motion, mobility, and can lead to considerable amount of post-operative pain for the patient. Amniotic membrane tissue has demonstrated clinical success as an anti-inflammatory and anti-scarring agent and promoting wound healing towards regeneration. Cryopreserved human amniotic membrane and umbilical cord (AM/UC) tissue in the form of CLARIX® CORD 1K has been used to treat over 5000 orthopedic patients. The investigators hypothesize that its use in peroneal and Achilles tendon surgical repair will enhance the overall functional recovery of the patient.

Peroneal and Achilles Tendon Tears

Amniox Medical, Inc.64 participantsStarted Feb 2016

Phoenix, Arizona, United States • Sun City West, Arizona, United States • Charlotte, North Carolina, United States +1 more locations

TERMINATEDPhase 132 miles

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

NCT03680560

This is a Phase 1, open-label, multi-center study to assess safety and determine the recommended phase 2 dose (RP2D) of ACTR T cell product (ACTR707 or ACTR087) in combination with trastuzumab, following lymphodepleting chemotherapy in subjects with HER2-positive advanced malignancies.

Solid TumorHER-2 Protein Overexpression

Cogent Biosciences, Inc.6 participantsStarted Mar 2019

New Haven, Connecticut, United States • Miami, Florida, United States • Columbus, Ohio, United States +3 more locations

Peroneal and Achilles Tendon Repair Indications With CLARIX® CORD 1K

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

Find Trials by Condition in Ohio

Safety Study of Eteplirsen to Treat Advanced Stage Duchenne Muscular Dystrophy

Efficacy Study of AVI-4658 to Induce Dystrophin Expression in Selected Duchenne Muscular Dystrophy Patients

Examining Heart Attacks in Young Women

Efficacy, Safety, and Tolerability Rollover Study of Eteplirsen in Subjects With Duchenne Muscular Dystrophy

TAU Opioid Use Outcomes Following Discharge From Detoxification and Short Term Residential Programs Affiliated With CTN-0051

Analyses of Human Samples Collected in Clinical Trials

Bendamustine and Dexamethasone in Patients With Relapsed AL Amyloidosis

Ofatumumab Bendamustine Combination Compared With Bendamustine Monotherapy in Indolent B-cell NHL Unresponsive to Rituxtherapy

Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin

Zero Degree Head Positioning in Hyperacute Large Artery Ischemic Stroke

Afatinib Treatment for Patients With EGFR Mutation Positive NSCLC Who Are Age 70 or Older

Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

Electrical Stimulation for the Treatment of Post-Amputation Pain Using the SPRINT System

Vaccine Therapy in Treating Patients With Breast Cancer

An 8-week, Open-label, Uncontrolled Study of Tamsulosin 0.4mg in Men With Bothersome Urinary Symptoms

Standard Root Planing vs. Periodontal Structure Repair Device for Treatment of Pockets Caused by Periodontal Disease

A Study of the Safety and Effectiveness of Liquid Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis

Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder