Clinical Trials in Ohio

Showing 9841-9860 of 20,938 trials

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

NCT03218683

This study is a multicenter, open-label, nonrandomized, sequential group, dose-escalation study to assess safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ascending doses of AZD5991 in subjects with relapsed or refractory hematologic malignancies Part 1 of the study is monotherapy dose escalation. Closed November 2020 Part 2 of the study is monotherapy expansion groups for relapsed/refractory chronic lymphocytic leukaemia (CLL), AML/ myelodysplastic syndromes (MDS), and multiple myeloma (MM). Closed November 2020 Part 3 is a sequential, dose-escalation study of the combination of AZD5991 and venetoclax in subjects with relapsed/refractory AML

Relapsed or Refractory Acute Myeloid Leukemia (AML)

AstraZeneca70 participantsStarted Aug 2017

Orange, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +7 more locations

COMPLETEDNA32 miles

Behavioral Economics and Adherence in Teens (BEAT!)

NCT03958331

Non-adherence to antiepileptic drug therapy is a significant problem for adolescents with epilepsy and has a critical impact on health and patient-reported outcomes. Evidence-based adherence interventions are lacking in this population and are critically needed. This proposal seeks to develop and evaluate a mHealth social norms adherence intervention for adolescents with epilepsy.

EpilepsyAdherence, Medication

Children's Hospital Medical Center, Cincinnati104 participantsStarted Sep 2019

Columbus, Ohio, United States

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

Behavioral Economics and Adherence in Teens (BEAT!)

Find Trials by Condition in Ohio

R2P Field Test of the EMS LiftKit: Validating Usability, Usefulness, Desirability, and Effects on Musculoskeletal Injuries in EMS Providers

KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC

Open Label Study of Long Term Evaluation Against LDL-C Trial

Study of Dalantercept and Sorafenib in Patients With Advanced Hepatocellular Carcinoma

Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing

A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

An Adaptive Study to Match Patients With Solid Tumors to Various Immunotherapy Combinations Based Upon a Broad Biomarker Assessment

Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma

A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.

An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesothelioma

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration

Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))

Natural History Study in Huntington Disease Gene Expansion Carriers (HDGECs) - SHIELD HD

SAR3419 in Acute Lymphoblastic Leukemia

Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)