Clinical Trials in Ohio

Showing 7261-7280 of 20,938 trials

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

NCT04434482

This is an open-label, multi-center, dose-escalation and dose-expansion phase I study to evaluate the safety, tolerability, PK characteristics and anti-tumor activity of PARP inhibitor IMP4297 and temozolomide combination therapy in patients with advanced solid tumors and with ES-SCLC who develops disease progression after 1L platinum-based regimen.

Advanced Solid TumoursSmall Cell Lung Cancer

Impact Therapeutics, Inc.59 participantsStarted Aug 2020

Evergreen Park, Illinois, United States • Canton, Ohio, United States • Columbus, Ohio, United States +18 more locations

TERMINATEDPhase 332 miles

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

NCT03955146

This is a Phase 3 trial to evaluate the efficacy and safety of 30 milligrams (mg)/kilogram (kg) intravenous (IV) infusions of pamrevlumab administered every 3 weeks as compared to placebo in participants with IPF.

Idiopathic Pulmonary Fibrosis

Kyntra Bio393 participantsStarted Jun 2019

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +122 more locations

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Find Trials by Condition in Ohio

A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)

Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1

A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A

A Safety, Tolerability and Pharmacokinetic Study of TAS-114 in Combination With Capecitabine in Patients With Advanced Solid Tumors

An Open-Label Extension Study for Patients With Duchenne Muscular Dystrophy Who Participated in Studies of SRP-5051 (Vesleteplirsen)

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

Randomized Controlled Trial for Vestibular Treatment in Concussion

Ammonia N-13 Myocardial Blood Flow Absolute Quantification by PET in Patients With Known or Suspected CAD (Ammonia MAP)

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

Evaluation of Sonelokimab for the Treatment of Patients With Active Psoriatic Arthritis

AI ENRICH - AI Detection of ICH

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

A Safety and Efficacy Study in Patients With Gastric Cancer

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control As a Means of Improving Glycemic Control in Adults with Type 2 Diabetes Mellitus

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients

Pilot Trial of the RUBI Program for Autistic Adults