Clinical Trials in Ohio

Showing 5361-5380 of 20,938 trials

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

NCT06139627

This clinical trial tests how well a geriatric assessment (GA) with GA-directed treatment recommendations, compared to GA with usual care, works in identifying risk factors, reducing chemotherapy radiation toxicity and functional decline, and improving the overall quality of life in older patients with non-small cell lung cancer (NSCLC). Older patients with lung cancer undergoing chemotherapy are at an increased risk of adverse outcomes including treatment toxicity and functional and physical consequences. This makes it very challenging for the physicians to balance the benefits against the risk of chemotherapy in older cancer patients. A geriatric assessment may be useful in identifying risk factors for chemotherapy radiation toxicity. Communicating these geriatric assessment findings and assessment-based recommendations to a patient's treating physicians may help them make more informed decisions about treatment options for patients. Making treatment decisions using GA-based recommendations may reduce adverse events and improve outcomes in patients receiving treatment for NSCLC.

Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8

City of Hope Medical Center180 participantsStarted May 2024

Duarte, California, United States • Rochester, New York, United States • Columbus, Ohio, United States

TERMINATEDPhase 281 miles

A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial Myopathy

NCT04641962

The purpose of this study was to evaluate the dose response of Bocidelpar on functional improvement relative to placebo, safety, and tolerability in participants with Primary Mitochondrial Myopathy.

Primary Mitochondrial Myopathy

Astellas Pharma Inc34 participantsStarted May 2021

La Jolla, California, United States • Stanford, California, United States • Aurora, Colorado, United States +8 more locations

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial Myopathy

Find Trials by Condition in Ohio

Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

STEM-PD Open Label Extension (OLE)

Human Amniotic Membrane On Venous Leg Ulcers In an Elderly Population

ROSE-Longitudinal Assessment With Neuroimaging

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

Study Testing Response Effect of KY1005 Against Moderate-to-Severe Atopic Dermatitis, The STREAM-AD Study

DOAC in Unusual Site Venous Thrombosis

DISSECT-N Post Market Data Collection Registry

Clinical Study of CMP-001 in Combination With Pembrolizumab or as a Monotherapy

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients

Blood Flow Restriction Training After Patellar INStability

An Open-label Study of Povetacicept in Participants With Autoimmune Cytopenias

Hydrogen's Feasibility and Safety as a Therapy in ECPR

Delivering Transcutaneous Auricular Neurostimulation to Improve Relapse Prevention in Opioid Use Disorder

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection

Rare Kidney Stone Consortium Patient Registry

Predicting Local and Distant Recurrence in T1 Colorectal Cancer

Stage II/III Colorectal Cancer Recurrence