Clinical Trials in Ohio

Showing 4141-4160 of 20,938 trials

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

NCT06377488

This will be an open-label, 3-visit, single-arm, dispensing clinical trial to evaluate visual acuity.

Johnson & Johnson Vision Care, Inc.176 participantsStarted Apr 2024

Jacksonville, Florida, United States • Jacksonville, Florida, United States • Longwood, Florida, United States +12 more locations

RECRUITINGPhase 232 miles

Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

NCT06824987

The purpose of this study is to assess the efficacy and safety of AZD2373 in participants diagnosed with APOL1-Mediated Kidney Disease (AMKD) who are homozygotes or compound heterozygotes for APOL1 high-risk genotypes (G1 and G2). The primary hypothesis to be evaluated is that AZD2373, compared with placebo, will result in a greater reduction in UACR as assessed by the relative change from Baseline in UACR at Week 30.

APOL1-Mediated Kidney Disease

AstraZeneca96 participantsStarted Mar 2025

Alabaster, Alabama, United States • Birmingham, Alabama, United States • Irondale, Alabama, United States +74 more locations

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

Find Trials by Condition in Ohio

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia

Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Determining Optimal Treatment Intensity for Children With Language Impairment

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

COVID-19 Study to Evaluate Safety, Tolerability, and Efficacy of REGN14256+Imdevimab for the Treatment of COVID-19 Adult and Adolescent Patients Without Risk Factors for Progression to Severe Disease

Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

CLIP-IT Post-Market Study

Gadopiclenol Pharmacokinetics, Safety and Efficacy in Children < 2 Years of Age

Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer

Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy

Efficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp Psoriasis

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

Pediatric Patients Aged 4 to 11 Years With APDS

Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP

Improving Risk Assessment of AML With a Precision Genomic Strategy to Assess Mutation Clearance

Safety and Pharmacokinetics Study of MBX 2109 in Adult Subjects With Normal and Impaired Renal Function

Stryker's Surgeon iD Mandible Reconstruction Plates: A Retrospective Post Market Follow Up