Clinical Trials in Ohio

Showing 3701-3720 of 20,938 trials

Safety and Effectiveness of the HIT Reverse HRS

NCT05357378

The purpose of this study is to determine if the use of the HIT Reverse Hip Replacement System is safe and effective in patients undergoing total hip replacement. We will determine whether it is safe and effective by comparing it to the control devices.

Degenerative Joint DiseaseOsteoarthritis, HipAvascular Necrosis of Hip+1 more

Hip Innovation Technology288 participantsStarted Jul 2022

Miami, Florida, United States • Tampa, Florida, United States • Tampa, Florida, United States +3 more locations

RECRUITINGPhase 132 miles

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

NCT06241456

This is a phase 1 study designed to evaluate the safety, tolerability, and antitumor activity of FT825 (also known as ONO-8250) with or without monoclonal antibody therapy following chemotherapy in participants with advanced human epidermal growth factor receptor 2 (HER2)-positive or other advanced solid tumors. The study will consist of a dose-escalation stage, followed by an expansion stage to further evaluate the safety and activity of FT825 in indication-specific cohorts.

Advanced Solid Tumor

Fate Therapeutics351 participantsStarted Jan 2024

Gilbert, Arizona, United States • La Jolla, California, United States • New Haven, Connecticut, United States +11 more locations

Safety and Effectiveness of the HIT Reverse HRS

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

Find Trials by Condition in Ohio

Weight, Energy, Lipids, and the Liver (WELL) Study

Re-Ablation Using a Tailored Approach Targeting EGM-Dispersion

MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC

A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors

A Research Study Looking at How Safe it is to Switch From Emicizumab to Mim8 in People With Haemophilia A (FRONTIER 5)

A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer

Study of BOTOX Injections in Prevention of Migraine in Adult Participants With Episodic Migraine

A Extension Study of Udenafil in Adolescents

A Dose-finding Study to Evaluate the Effect of a Contraceptive Vaginal Ring, Releasing Nestorone® and Estradiol, on Cycle Control, Ovulation Inhibition, and Pharmacokinetics in Normal Cycling Women

Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer

Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma

Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations

A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)

Chyme Reinfusion for Type 2 Intestinal Failure

An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

Acalabrutinib (ACP-196) in Combination With ACP-319, for Treatment of B-Cell Malignancies

Tube Size Randomized Trial During Emergency Tracheal Intubation

Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations